Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2359703..2359908 Replicon chromosome
Accession NZ_CP014791
Organism Staphylococcus aureus strain MCRF184

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag CKU_RS11820 Protein ID WP_000482647.1
Coordinates 2359801..2359908 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2359703..2359757 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CKU_RS11795 2355289..2355456 - 168 WP_031785511.1 hypothetical protein -
CKU_RS11805 2355687..2357420 - 1734 WP_000488492.1 ABC transporter ATP-binding protein/permease -
CKU_RS11810 2357469..2359208 - 1740 WP_001064831.1 ABC transporter ATP-binding protein/permease -
CKU_RS11815 2359586..2359774 - 189 WP_061869756.1 hypothetical protein -
- 2359703..2359757 + 55 - - Antitoxin
CKU_RS11820 2359801..2359908 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
CKU_RS11825 2360042..2360428 - 387 WP_000779354.1 flippase GtxA -
CKU_RS11830 2360696..2361838 + 1143 WP_001176860.1 glycerate kinase -
CKU_RS11835 2361898..2362557 + 660 WP_000831298.1 membrane protein -
CKU_RS11840 2362737..2363948 + 1212 WP_001191975.1 multidrug effflux MFS transporter -
CKU_RS11845 2364071..2364544 - 474 WP_000456491.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T61812 WP_000482647.1 NZ_CP014791:c2359908-2359801 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T61812 NZ_CP014791:c2359908-2359801 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 55 bp

>AT61812 NZ_CP014791:2359703-2359757 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCTAAATAAATCCCCTCACTACTGCCA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References