Detailed information of TA system TA061799

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): yefM-yoeB (relBE)/YoeB-RelB
• Location: 15554..16065
• Replicon: chromosome
• Accession: NZ_CP014782
• Organism: Shewanella psychrophila strain WP2

Toxin (Protein)

• Gene name: yoeB
• Uniprot ID: -
• Locus tag: sps_RS00080
• Protein ID: WP_077750611.1
• Coordinates: 15554..15814 (-)
• Length: 87 a.a.

Antitoxin (Protein)

• Gene name: yefM
• Uniprot ID: -
• Locus tag: sps_RS00085
• Protein ID: WP_077750612.1
• Coordinates: 15814..16065 (-)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
sps_RS00065	12060..12260	+	201	WP_077750608.1	hypothetical protein	-
sps_RS00070	13028..14242	+	1215	WP_077750609.1	winged helix DNA-binding domain-containing protein	-
sps_RS00075	14602..15543	+	942	WP_077750610.1	DUF1186 domain-containing protein	-
sps_RS00080	15554..15814	-	261	WP_077750611.1	Txe/YoeB family addiction module toxin	Toxin
sps_RS00085	15814..16065	-	252	WP_077750612.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
sps_RS00090	16698..18296	-	1599	WP_077750613.1	DNA cytosine methyltransferase	-
sps_RS00095	18579..20048	+	1470	Protein_18	hypothetical protein	-
sps_RS00100	20192..20398	+	207	WP_179948389.1	hypothetical protein	-
sps_RS28410	20458..20598	+	141	WP_169915616.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (5-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-73)

Sequences

Toxin

Protein

• Length: 87 a.a.
• Molecular weight: 10409.88 Da
• Isoelectric Point: 9.8630

>T61799 WP_077750611.1 NZ_CP014782:c15814-15554 [Shewanella psychrophila]
MNILFSDNAWNDYLYWQQQDKKTLKRINLLIKDCQRTPFEGIGKPERLKENLSGYWSRRITDEHRLVYKATQDKLTIVAV
RYHYSS

Nucleotide

• Length: 261 bp

>T61799 NZ_CP014782:c15814-15554 [Shewanella psychrophila]
ATGAATATTCTCTTCTCTGATAACGCCTGGAATGATTACCTTTATTGGCAACAACAAGATAAAAAAACATTGAAACGAAT
TAACCTGCTTATTAAAGATTGCCAAAGGACACCTTTTGAAGGTATCGGCAAACCAGAAAGGTTAAAAGAGAACCTTTCTG
GTTATTGGTCTAGACGGATCACCGATGAACATCGTTTAGTTTATAAGGCGACTCAGGATAAGTTAACGATCGTTGCCGTA
CGCTATCACTACTCTTCCTAA

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9447.56 Da
• Isoelectric Point: 4.4475

>AT61799 WP_077750612.1 NZ_CP014782:c16065-15814 [Shewanella psychrophila]
MSVYSFTEVRSNLKSVCDSVVNDCEPAVIHRRGAENVVMFSESEFNSWKETIYLLSNPVNAKHLLDSIKQVEDGQAQERE
LLD

Nucleotide

• Length: 252 bp

>AT61799 NZ_CP014782:c16065-15814 [Shewanella psychrophila]
ATGAGTGTTTATAGTTTTACCGAGGTTAGAAGTAACCTTAAATCGGTCTGTGACAGCGTGGTCAACGACTGCGAACCTGC
GGTGATCCACCGTAGAGGTGCTGAAAATGTTGTCATGTTTTCAGAGTCAGAGTTCAATAGCTGGAAAGAAACTATCTACT
TACTTTCAAACCCAGTAAATGCAAAGCATCTGCTAGATTCTATAAAGCAGGTTGAAGATGGCCAAGCTCAAGAGCGTGAG
TTACTGGATTAA