61719

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) virAT/YafQ(toxin)
Location 23598..24147 Replicon plasmid pCJDM67 S
Accession NZ_CP014746
Organism Campylobacter jejuni strain OD267

Toxin (Protein)


Gene name virT Uniprot ID A0A5T0ZCU7
Locus tag A0W68_RS09615 Protein ID WP_014517465.1
Coordinates 23598..23873 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name virA Uniprot ID A0A5T1T0M3
Locus tag A0W68_RS09620 Protein ID WP_014517464.1
Coordinates 23863..24147 (-) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A0W68_RS09595 19916..20158 - 243 WP_011117593.1 hypothetical protein -
A0W68_RS09600 20158..20463 - 306 WP_011799398.1 hypothetical protein -
A0W68_RS09605 21294..22865 + 1572 WP_057993425.1 relaxase/mobilization nuclease domain-containing protein -
A0W68_RS09610 23092..23484 - 393 WP_014517466.1 hypothetical protein -
A0W68_RS09615 23598..23873 - 276 WP_014517465.1 type II toxin-antitoxin system YafQ family toxin Toxin
A0W68_RS09620 23863..24147 - 285 WP_014517464.1 hypothetical protein Antitoxin
A0W68_RS09625 24371..24733 - 363 WP_011117587.1 hypothetical protein -
A0W68_RS09630 24944..25246 - 303 WP_025443373.1 hypothetical protein -
A0W68_RS09635 25246..25677 - 432 WP_057039947.1 hypothetical protein -
A0W68_RS09640 25674..26084 - 411 WP_057993424.1 hypothetical protein -
A0W68_RS09645 26101..26322 - 222 WP_011799395.1 hypothetical protein -
A0W68_RS09650 26332..26640 - 309 WP_057993423.1 hypothetical protein -
A0W68_RS09655 26654..26998 - 345 WP_024266121.1 hypothetical protein -
A0W68_RS09660 27470..27898 - 429 WP_061577931.1 hypothetical protein -
A0W68_RS09665 27904..29136 - 1233 WP_102134673.1 toprim domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Non-Mobilizable plasmid - virD4 / virB11 / virB10 / virB9 / virB8 / Cjp54 / virB4 1..36602 36602


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(4-91)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10872.64 Da        Isoelectric Point: 10.2009

>T61719 WP_014517465.1 NZ_CP014746:c23873-23598 [Campylobacter jejuni]
MQNKYSVTFSKRFKKDFKKINNNDKKILKKIVNKLANDEVLEEKYKDHALKGNYIGFRECHIKPDLLLVYRKNNDILELY
LANLGNHNNIF

Download         Length: 276 bp

>T61719 NZ_CP014746:c23873-23598 [Campylobacter jejuni]
ATGCAGAATAAATATAGCGTTACTTTTTCTAAAAGGTTTAAAAAAGATTTTAAAAAAATAAATAATAATGATAAAAAAAT
TTTAAAAAAAATAGTCAATAAACTTGCCAATGATGAAGTATTAGAAGAAAAATACAAAGACCACGCACTAAAAGGAAATT
ATATCGGTTTTAGAGAATGCCACATTAAACCTGATTTGTTATTAGTCTATCGCAAAAATAATGATATTTTAGAATTATAT
TTGGCTAATTTAGGAAATCACAATAATATTTTTTAG

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 11082.46 Da        Isoelectric Point: 8.3991

>AT61719 WP_014517464.1 NZ_CP014746:c24147-23863 [Campylobacter jejuni]
MFDYSKYENATEKQLIHALTLAEKRAEKLNSQLKENNELFKFLQKKLKNSFNTKKTKKADQRRPELDEAIEDYKNGNVEH
YANVEEAFKALNAE

Download         Length: 285 bp

>AT61719 NZ_CP014746:c24147-23863 [Campylobacter jejuni]
ATGTTTGATTATTCTAAATATGAAAATGCTACTGAAAAACAATTAATACACGCTTTGACTTTAGCAGAAAAAAGAGCAGA
GAAACTAAACTCGCAATTAAAAGAGAATAACGAACTTTTTAAATTTTTACAAAAAAAGTTAAAAAATTCTTTTAACACCA
AAAAAACAAAAAAAGCAGATCAAAGAAGACCTGAATTAGATGAAGCGATTGAAGATTATAAAAATGGAAATGTAGAACAT
TATGCCAATGTAGAAGAAGCGTTTAAGGCTTTAAATGCAGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A5T0ZCU7

Antitoxin

Source ID Structure
AlphaFold DB A0A5T1T0M3

References