Detailed information of TA system TA061719

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): virAT/YafQ(toxin)
• Location: 23598..24147
• Replicon: plasmid pCJDM67 S
• Accession: NZ_CP014746
• Organism: Campylobacter jejuni strain OD267

Toxin (Protein)

• Gene name: virT
• Uniprot ID: A0A5T0ZCU7
• Locus tag: A0W68_RS09615
• Protein ID: WP_014517465.1
• Coordinates: 23598..23873 (-)
• Length: 92 a.a.

Antitoxin (Protein)

• Gene name: virA
• Uniprot ID: A0A5T1T0M3
• Locus tag: A0W68_RS09620
• Protein ID: WP_014517464.1
• Coordinates: 23863..24147 (-)
• Length: 95 a.a.

Genomic Context

Location: 21294..22865 (1572 bp)
Type: Others
Protein ID: WP_057993425.1

Location: 19916..20158 (243 bp)
Type: Others
Protein ID: WP_011117593.1

Location: 20158..20463 (306 bp)
Type: Others
Protein ID: WP_011799398.1

Location: 23092..23484 (393 bp)
Type: Others
Protein ID: WP_014517466.1

Location: 23598..23873 (276 bp)
Type: Toxin
Protein ID: WP_014517465.1

Location: 23863..24147 (285 bp)
Type: Antitoxin
Protein ID: WP_014517464.1

Location: 24371..24733 (363 bp)
Type: Others
Protein ID: WP_011117587.1

Location: 24944..25246 (303 bp)
Type: Others
Protein ID: WP_025443373.1

Location: 25246..25677 (432 bp)
Type: Others
Protein ID: WP_057039947.1

Location: 25674..26084 (411 bp)
Type: Others
Protein ID: WP_057993424.1

Location: 26101..26322 (222 bp)
Type: Others
Protein ID: WP_011799395.1

Location: 26332..26640 (309 bp)
Type: Others
Protein ID: WP_057993423.1

Location: 26654..26998 (345 bp)
Type: Others
Protein ID: WP_024266121.1

Location: 27470..27898 (429 bp)
Type: Others
Protein ID: WP_061577931.1

Location: 27904..29136 (1233 bp)
Type: Others
Protein ID: WP_102134673.1

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Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
A0W68_RS09595	19916..20158	-	243	WP_011117593.1	hypothetical protein	-
A0W68_RS09600	20158..20463	-	306	WP_011799398.1	hypothetical protein	-
A0W68_RS09605	21294..22865	+	1572	WP_057993425.1	relaxase/mobilization nuclease domain-containing protein	-
A0W68_RS09610	23092..23484	-	393	WP_014517466.1	hypothetical protein	-
A0W68_RS09615	23598..23873	-	276	WP_014517465.1	type II toxin-antitoxin system YafQ family toxin	Toxin
A0W68_RS09620	23863..24147	-	285	WP_014517464.1	hypothetical protein	Antitoxin
A0W68_RS09625	24371..24733	-	363	WP_011117587.1	hypothetical protein	-
A0W68_RS09630	24944..25246	-	303	WP_025443373.1	hypothetical protein	-
A0W68_RS09635	25246..25677	-	432	WP_057039947.1	hypothetical protein	-
A0W68_RS09640	25674..26084	-	411	WP_057993424.1	hypothetical protein	-
A0W68_RS09645	26101..26322	-	222	WP_011799395.1	hypothetical protein	-
A0W68_RS09650	26332..26640	-	309	WP_057993423.1	hypothetical protein	-
A0W68_RS09655	26654..26998	-	345	WP_024266121.1	hypothetical protein	-
A0W68_RS09660	27470..27898	-	429	WP_061577931.1	hypothetical protein	-
A0W68_RS09665	27904..29136	-	1233	WP_102134673.1	toprim domain-containing protein	-

Associated MGEs

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MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	Similar MGE(s) Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE. Detail Genome accession Organism MGE type Related TA Coordinates Mash distance View NC_017284 Campylobacter jejuni subsp. jejuni IA3902 Non-Mobilizable plasmid TA006286 1..37174 0.007	inside	Non-Mobilizable plasmid	-	virD4 / virB11 / virB10 / virB9 / virB8 / Cjp54 / virB4	1..36602	36602

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, YafQ-like toxin (4-91)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 92 a.a.
• Molecular weight: 10872.64 Da
• Isoelectric Point: 10.2009

>T61719 WP_014517465.1 NZ_CP014746:c23873-23598 [Campylobacter jejuni]
MQNKYSVTFSKRFKKDFKKINNNDKKILKKIVNKLANDEVLEEKYKDHALKGNYIGFRECHIKPDLLLVYRKNNDILELY
LANLGNHNNIF

Nucleotide

• Length: 276 bp

>T61719 NZ_CP014746:c23873-23598 [Campylobacter jejuni]
ATGCAGAATAAATATAGCGTTACTTTTTCTAAAAGGTTTAAAAAAGATTTTAAAAAAATAAATAATAATGATAAAAAAAT
TTTAAAAAAAATAGTCAATAAACTTGCCAATGATGAAGTATTAGAAGAAAAATACAAAGACCACGCACTAAAAGGAAATT
ATATCGGTTTTAGAGAATGCCACATTAAACCTGATTTGTTATTAGTCTATCGCAAAAATAATGATATTTTAGAATTATAT
TTGGCTAATTTAGGAAATCACAATAATATTTTTTAG

Antitoxin

Protein

• Length: 95 a.a.
• Molecular weight: 11082.46 Da
• Isoelectric Point: 8.3991

>AT61719 WP_014517464.1 NZ_CP014746:c24147-23863 [Campylobacter jejuni]
MFDYSKYENATEKQLIHALTLAEKRAEKLNSQLKENNELFKFLQKKLKNSFNTKKTKKADQRRPELDEAIEDYKNGNVEH
YANVEEAFKALNAE

Nucleotide

• Length: 285 bp

>AT61719 NZ_CP014746:c24147-23863 [Campylobacter jejuni]
ATGTTTGATTATTCTAAATATGAAAATGCTACTGAAAAACAATTAATACACGCTTTGACTTTAGCAGAAAAAAGAGCAGA
GAAACTAAACTCGCAATTAAAAGAGAATAACGAACTTTTTAAATTTTTACAAAAAAAGTTAAAAAATTCTTTTAACACCA
AAAAAACAAAAAAAGCAGATCAAAGAAGACCTGAATTAGATGAAGCGATTGAAGATTATAAAAATGGAAATGTAGAACAT
TATGCCAATGTAGAAGAAGCGTTTAAGGCTTTAAATGCAGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Toxin

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Protein	Organism	Identities (%)	Coverage (%)	Ha-value
No matching records found

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Antitoxin

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Protein	Organism	Identities (%)	Coverage (%)	Ha-value
No matching records found

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Structures

Toxin

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• AlphaFold DB: A0A5T0ZCU7

Antitoxin

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• AlphaFold DB: A0A5T1T0M3