Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 4979710..4979973 Replicon chromosome
Accession NZ_CP014608
Organism Obesumbacterium proteus strain DSM 2777

Toxin (Protein)


Gene name hokH Uniprot ID A0A1C6YY26
Locus tag DSM2777_RS24000 Protein ID WP_025798685.1
Coordinates 4979710..4979868 (-) Length 53 a.a.

Antitoxin (RNA)


Gene name sokH
Locus tag -
Coordinates 4979921..4979973 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DSM2777_RS23340 4974870..4975403 - 534 WP_061555263.1 SprT family zinc-dependent metalloprotease -
DSM2777_RS23345 4975896..4977224 + 1329 WP_061555264.1 cadaverine/lysine antiporter -
DSM2777_RS23350 4977330..4979549 + 2220 WP_025798687.1 lysine decarboxylase -
DSM2777_RS24000 4979710..4979868 - 159 WP_025798685.1 Hok/Gef family protein Toxin
- 4979921..4979973 + 53 - - Antitoxin
DSM2777_RS23355 4980136..4981296 - 1161 WP_061555265.1 glutathionylspermidine synthase family protein -
DSM2777_RS23360 4981299..4981982 - 684 WP_043490623.1 DUF1190 family protein -
DSM2777_RS23365 4982488..4983588 + 1101 WP_061555266.1 glycerol dehydrogenase -
DSM2777_RS23370 4983688..4984758 + 1071 WP_061555267.1 dihydroxyacetone kinase subunit DhaK -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(6-46)


Sequences

Toxin        


Download         Length: 53 a.a.        Molecular weight: 6065.37 Da        Isoelectric Point: 9.2226

>T61561 WP_025798685.1 NZ_CP014608:c4979868-4979710 [Obesumbacterium proteus]
MSRKLLLYGLIVMCFTLLIFTWMVRGSLCELRIKQGKTEVAAFLNYEDKHAL

Download         Length: 159 bp

>T61561 NZ_CP014608:c4979868-4979710 [Obesumbacterium proteus]
ATGTCGCGTAAGCTGTTGCTTTATGGATTAATAGTGATGTGTTTTACGCTATTGATCTTTACCTGGATGGTACGTGGTTC
GCTGTGCGAGCTACGAATTAAGCAGGGAAAAACAGAGGTTGCCGCGTTCTTAAACTACGAAGATAAGCACGCGTTGTAA

Antitoxin


Download         Length: 53 bp

>AT61561 NZ_CP014608:4979921-4979973 [Obesumbacterium proteus]
GATGTGGTTAGGATTGCCTCAGGTTAATGAAAATTGACCTGGGGCTTTTACTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1C6YY26

Antitoxin

Download structure file

References