Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 1063056..1063756 Replicon chromosome
Accession NZ_CP014579
Organism Paraburkholderia phytofirmans OLGA172

Toxin (Protein)


Gene name mqsR Uniprot ID A0A160FSJ7
Locus tag AYM40_RS25035 Protein ID WP_063498891.1
Coordinates 1063056..1063352 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID A0A160FRI1
Locus tag AYM40_RS25040 Protein ID WP_063498892.1
Coordinates 1063355..1063756 (+) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AYM40_RS25025 1058692..1060119 + 1428 WP_063498889.1 NAD-dependent succinate-semialdehyde dehydrogenase -
AYM40_RS25030 1060385..1062889 - 2505 WP_063498890.1 FAD-dependent oxidoreductase -
AYM40_RS25035 1063056..1063352 + 297 WP_063498891.1 type II toxin-antitoxin system MqsR family toxin Toxin
AYM40_RS25040 1063355..1063756 + 402 WP_063498892.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
AYM40_RS25045 1063861..1064694 + 834 WP_063498893.1 DeoR/GlpR family DNA-binding transcription regulator -
AYM40_RS25050 1064937..1068443 + 3507 WP_063498894.1 DEAD/DEAH box helicase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(5-97)

Antitoxin

Antitoxin MqsA/HigA-2

(1-131)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 10724.58 Da        Isoelectric Point: 8.7284

>T61512 WP_063498891.1 NZ_CP014579:1063056-1063352 [Paraburkholderia phytofirmans OLGA172]
VEKNTPHCKLADVQGLVRAGKVRITKSAVIGAAALGLGPAAIVETLMSLDRRQFRKSMTTYADHRVWQDVYCAVTEAGMV
YLKLTVVDDVLVVSFKEC

Download         Length: 297 bp

>T61512 NZ_CP014579:1063056-1063352 [Paraburkholderia phytofirmans OLGA172]
GTGGAAAAAAATACGCCTCACTGCAAATTGGCAGATGTCCAGGGCCTGGTGCGCGCAGGGAAGGTCAGAATCACGAAATC
GGCCGTGATTGGGGCTGCGGCACTCGGCCTCGGACCTGCAGCAATCGTCGAAACGTTGATGTCGCTTGATCGGCGCCAAT
TCAGAAAAAGCATGACCACGTACGCGGATCACCGGGTCTGGCAGGACGTCTACTGCGCCGTGACTGAAGCAGGCATGGTC
TATTTGAAATTGACGGTGGTCGATGACGTCCTCGTCGTGTCATTCAAGGAGTGCTGA

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14712.89 Da        Isoelectric Point: 5.2875

>AT61512 WP_063498892.1 NZ_CP014579:1063355-1063756 [Paraburkholderia phytofirmans OLGA172]
MKCPNCGAAELVRDTRNMRYVYKGETAIFEAVTGDYCPACEEAVLDMDEATRTGQMMLAFNKEVNASQVDPAFISAVRKK
LDLDQREAAEIFGGGVNAFSRYENGKTRPPLALIKLLKVLDRHPELLAEVRAG

Download         Length: 402 bp

>AT61512 NZ_CP014579:1063355-1063756 [Paraburkholderia phytofirmans OLGA172]
ATGAAATGTCCGAACTGCGGAGCGGCCGAACTGGTGCGCGATACGCGCAATATGCGCTATGTCTACAAGGGGGAGACGGC
CATCTTCGAGGCCGTCACTGGCGACTATTGCCCGGCATGCGAAGAGGCGGTGCTCGACATGGACGAGGCGACCCGCACGG
GTCAAATGATGCTGGCCTTCAACAAAGAGGTGAATGCATCGCAAGTGGATCCCGCCTTCATTTCCGCCGTACGCAAGAAG
CTTGATCTGGACCAGCGCGAGGCAGCAGAAATTTTCGGCGGCGGGGTGAACGCTTTTTCGCGGTACGAGAATGGCAAGAC
CAGGCCACCGCTCGCGCTTATCAAGCTGTTGAAGGTGCTGGATCGGCACCCGGAGCTGCTGGCGGAAGTGAGGGCGGGCT
GA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A160FSJ7

Antitoxin

Source ID Structure
AlphaFold DB A0A160FRI1

References