61510

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 885400..885955 Replicon chromosome
Accession NZ_CP014579
Organism Paraburkholderia phytofirmans OLGA172

Toxin (Protein)


Gene name yoeB Uniprot ID A0A160FRP0
Locus tag AYM40_RS24250 Protein ID WP_063498758.1
Coordinates 885704..885955 (+) Length 84 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A160FRL2
Locus tag AYM40_RS24245 Protein ID WP_063498757.1
Coordinates 885400..885693 (+) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AYM40_RS24230 881183..882853 - 1671 WP_063498754.1 malonate decarboxylase subunit alpha -
AYM40_RS24235 882862..883635 - 774 WP_063498755.1 GntR family transcriptional regulator -
AYM40_RS24240 883835..885133 + 1299 WP_063498756.1 MFS transporter -
AYM40_RS24245 885400..885693 + 294 WP_063498757.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
AYM40_RS24250 885704..885955 + 252 WP_063498758.1 Txe/YoeB family addiction module toxin Toxin
AYM40_RS24255 886001..886921 - 921 WP_063498759.1 DMT family transporter -
AYM40_RS24260 887036..887923 + 888 WP_063498760.1 LysR family transcriptional regulator -
AYM40_RS24265 888064..889122 - 1059 WP_063498761.1 ABC transporter ATP-binding protein -
AYM40_RS24270 889162..890766 - 1605 WP_063498762.1 iron ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(2-81)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 84 a.a.        Molecular weight: 10004.27 Da        Isoelectric Point: 6.7084

>T61510 WP_063498758.1 NZ_CP014579:885704-885955 [Paraburkholderia phytofirmans OLGA172]
MFTDEAWDDYLYWQETDRKVLHKINTLLEECRRDPYRGTGKPEALVGSLSGFWSRRITHADRLVYLPRDGKIYVFACRFH
YDD

Download         Length: 252 bp

>T61510 NZ_CP014579:885704-885955 [Paraburkholderia phytofirmans OLGA172]
ATGTTCACGGACGAAGCGTGGGACGACTACCTGTACTGGCAGGAGACTGATCGAAAGGTCTTACACAAGATCAATACGCT
GCTAGAGGAGTGTCGGCGCGATCCCTATCGCGGTACTGGAAAGCCAGAAGCGCTGGTGGGCAGCTTAAGCGGTTTCTGGT
CGCGACGTATCACTCACGCTGATCGACTGGTTTATTTGCCGAGAGACGGAAAGATCTATGTGTTCGCTTGCCGTTTCCAC
TACGACGACTAA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10695.02 Da        Isoelectric Point: 5.8125

>AT61510 WP_063498757.1 NZ_CP014579:885400-885693 [Paraburkholderia phytofirmans OLGA172]
MNVLTYSEARAGFKQAMDDVCRDHTPMLITRQSGENVVMVSLEDFNAMQETLYLLSSSKNAQRLAKSIAQLNAGGATSRD
LLTDEQTEKLQRGGRNG

Download         Length: 294 bp

>AT61510 NZ_CP014579:885400-885693 [Paraburkholderia phytofirmans OLGA172]
ATGAACGTCCTTACTTATAGCGAGGCCCGCGCCGGCTTTAAGCAAGCGATGGACGACGTTTGCCGCGATCACACGCCCAT
GCTGATAACCCGGCAGAGCGGCGAAAATGTGGTCATGGTTTCGCTCGAGGATTTCAATGCGATGCAGGAAACCTTGTATC
TGTTGAGTTCATCGAAGAACGCCCAGCGGCTTGCCAAATCTATCGCTCAGTTGAATGCCGGCGGTGCGACTTCGCGCGAC
CTGCTGACCGATGAACAAACAGAAAAGCTGCAACGAGGAGGCCGCAACGGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A160FRP0

Antitoxin

Source ID Structure
AlphaFold DB A0A160FRL2

References