Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 5611405..5612059 Replicon chromosome
Accession NZ_CP014546
Organism Pseudomonas azotoformans strain S4

Toxin (Protein)


Gene name higB Uniprot ID A0A127I3Q8
Locus tag AYR47_RS25685 Protein ID WP_033896842.1
Coordinates 5611405..5611755 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID W2E036
Locus tag AYR47_RS25690 Protein ID WP_033896843.1
Coordinates 5611745..5612059 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AYR47_RS25675 5608163..5609695 + 1533 WP_010209575.1 NADH-quinone oxidoreductase subunit M -
AYR47_RS25680 5609703..5611166 + 1464 WP_033896841.1 NADH-quinone oxidoreductase subunit NuoN -
AYR47_RS25685 5611405..5611755 + 351 WP_033896842.1 toxin Toxin
AYR47_RS25690 5611745..5612059 + 315 WP_033896843.1 XRE family transcriptional regulator Antitoxin
AYR47_RS25695 5612095..5612640 - 546 WP_033896845.1 type VI secretion system-associated protein TagF -
AYR47_RS25700 5612650..5616213 - 3564 WP_061448905.1 type VI secretion system membrane subunit TssM -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 13798.68 Da        Isoelectric Point: 9.3125

>T61438 WP_033896842.1 NZ_CP014546:5611405-5611755 [Pseudomonas azotoformans]
MDALFIELPAFERHRKDYLSDELFQGFQQELMKNPEAGDVIEGTGGLRKVRFVDERRNKGKRGGLRVIYYWWSGGTQFWL
FTLYGKHEQDDLTPQHKKALKHLLDREIKARTHYET

Download         Length: 351 bp

>T61438 NZ_CP014546:5611405-5611755 [Pseudomonas azotoformans]
ATGGATGCTCTATTTATCGAACTGCCGGCCTTCGAGCGGCATCGCAAGGACTATCTGAGTGACGAGCTTTTCCAGGGTTT
TCAACAAGAGTTGATGAAAAACCCGGAAGCAGGAGATGTGATCGAGGGAACAGGCGGACTGCGCAAGGTTCGCTTCGTCG
ATGAGCGGCGCAACAAAGGCAAGCGCGGTGGCCTGCGGGTCATTTACTACTGGTGGTCGGGCGGCACGCAATTCTGGCTG
TTCACCCTGTACGGCAAGCACGAACAGGATGACCTGACACCACAGCACAAAAAAGCCCTAAAACACCTGCTGGACAGGGA
AATCAAAGCGAGAACACATTATGAAACGTGA

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11714.52 Da        Isoelectric Point: 10.6525

>AT61438 WP_033896843.1 NZ_CP014546:5611745-5612059 [Pseudomonas azotoformans]
MKREIFSELVEGFDALADERQGKVTLRTHKVHLKNLAPLTAEEVVAVRQQLNLSRSVFAMYLRTNTRTLENWEQGRAKPN
AQAATLIRLVARFPETVAQLAALG

Download         Length: 315 bp

>AT61438 NZ_CP014546:5611745-5612059 [Pseudomonas azotoformans]
ATGAAACGTGAAATCTTTTCCGAACTGGTCGAAGGCTTCGACGCCCTGGCAGACGAACGCCAAGGCAAAGTCACCCTGCG
AACCCACAAGGTTCACCTCAAAAACCTGGCGCCACTCACCGCCGAGGAAGTGGTCGCGGTGCGCCAACAACTCAACCTCT
CCCGGTCGGTGTTCGCCATGTACCTGCGCACCAACACCCGCACCCTGGAAAACTGGGAGCAAGGCCGGGCCAAGCCGAAC
GCCCAGGCTGCTACGCTGATCCGCCTGGTGGCACGTTTCCCGGAAACCGTGGCGCAACTTGCTGCATTGGGTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A127I3Q8

Antitoxin

Source ID Structure
AlphaFold DB A0A7Y8KJ45

References