Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) DinJ-YafQ (relBE)/YafQ-RelB
Location 283850..284382 Replicon plasmid unnamed 2
Accession NZ_CP014527
Organism Haematospirillum jordaniae strain H5569

Toxin (Protein)


Gene name yafQ Uniprot ID A0A143DG99
Locus tag AY555_RS11345 Protein ID WP_066137009.1
Coordinates 283850..284122 (-) Length 91 a.a.

Antitoxin (Protein)


Gene name dinJ Uniprot ID A0A143DH71
Locus tag AY555_RS11350 Protein ID WP_066137371.1
Coordinates 284122..284382 (-) Length 87 a.a.

Genomic Context

AY555_RS11320AY555_RS11335AY555_RS11355AY555_RS11360AY555_RS11375AY555_RS11325AY555_RS11330AY555_RS11340AY555_RS11345AY555_RS11350AY555_RS11365AY555_RS11370
Location: 279446..280648 (1203 bp)
Type: Others
Protein ID: WP_066133065.1
Location: 282418..283428 (1011 bp)
Type: Others
Protein ID: WP_066137004.1
Location: 284607..285248 (642 bp)
Type: Others
Protein ID: WP_066137011.1
Location: 285288..285554 (267 bp)
Type: Others
Protein ID: WP_066137013.1
Location: 288427..288810 (384 bp)
Type: Others
Protein ID: WP_066137018.1
Location: 280705..281385 (681 bp)
Type: Others
Protein ID: WP_167798514.1
Location: 281730..282006 (277 bp)
Type: Others
Protein ID: Protein_238
Location: 283425..283679 (255 bp)
Type: Others
Protein ID: WP_066137006.1
Location: 283850..284122 (273 bp)
Type: Toxin
Protein ID: WP_066137009.1
Location: 284122..284382 (261 bp)
Type: Antitoxin
Protein ID: WP_066137371.1
Location: 285672..287378 (1707 bp)
Type: Others
Protein ID: WP_066137015.1
Location: 287458..287793 (336 bp)
Type: Others
Protein ID: WP_066137017.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
AY555_RS11320279446..280648+1203WP_066133065.1transposase-
AY555_RS11325280705..281385-681WP_167798514.1hypothetical protein-
AY555_RS11330281730..282006-277Protein_238single-stranded DNA-binding protein-
AY555_RS11335282418..283428+1011WP_066137004.1calcium-binding protein-
AY555_RS11340283425..283679-255WP_066137006.1phage major tail tube protein-
AY555_RS11345283850..284122-273WP_066137009.1type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE familyToxin
AY555_RS11350284122..284382-261WP_066137371.1type II toxin-antitoxin system RelB/DinJ family antitoxinAntitoxin
AY555_RS11355284607..285248+642WP_066137011.1AAA family ATPase-
AY555_RS11360285288..285554+267WP_066137013.1ribbon-helix-helix domain-containing protein-
AY555_RS11365285672..287378-1707WP_066137015.1recombinase family protein-
AY555_RS11370287458..287793-336WP_066137017.1hypothetical protein-
AY555_RS11375288427..288810+384WP_066137018.1MbcA/ParS/Xre antitoxin family protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideNon-Mobilizable plasmid-ugd1..303116303116


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-88)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(3-84)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10568.13 Da        Isoelectric Point: 10.2626

>T61403 WP_066137009.1 NZ_CP014527:c284122-283850 [Haematospirillum jordaniae]
MRHPEYSGQFKRDVKASGRRGKDMSKLKVLIELLIAGTPLPATYLDHPLKGRWRSYRDAHIESDWLLIYKINGNVVRFER
TGRHTDLFDE

Download         Length: 273 bp

>T61403 NZ_CP014527:c284122-283850 [Haematospirillum jordaniae]
ATGCGGCACCCGGAGTATTCTGGCCAGTTCAAGCGTGACGTCAAGGCTTCTGGAAGGCGTGGCAAGGACATGAGCAAGCT
CAAGGTTCTGATAGAGCTGCTGATAGCAGGTACGCCGTTGCCTGCCACGTATCTCGACCACCCGCTTAAAGGGCGGTGGC
GTAGCTACCGGGATGCCCACATTGAGTCGGACTGGCTTCTGATCTACAAAATCAATGGCAATGTTGTCCGCTTTGAACGA
ACTGGACGGCACACCGATCTTTTCGACGAATAA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9257.61 Da        Isoelectric Point: 5.5882

>AT61403 WP_066137371.1 NZ_CP014527:c284382-284122 [Haematospirillum jordaniae]
MKANAFVRARIDETLKNEAAAVLAGMGLTVSDVVRIALTKIAKEKTLPFDMRVPNALTAETLAKSEHGEDVHHANDADDL
FAQLGI

Download         Length: 261 bp

>AT61403 NZ_CP014527:c284382-284122 [Haematospirillum jordaniae]
ATGAAAGCAAATGCATTTGTCCGCGCCCGGATCGACGAGACGCTAAAAAACGAAGCCGCTGCCGTACTGGCGGGTATGGG
GCTTACTGTGTCCGATGTAGTGCGCATTGCCCTCACCAAAATCGCCAAAGAAAAGACGCTGCCATTCGACATGCGCGTTC
CTAACGCACTGACGGCGGAAACGCTGGCGAAAAGTGAGCATGGTGAAGATGTTCACCATGCCAACGATGCGGATGATCTG
TTTGCCCAGCTGGGTATTTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A143DG99

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A143DH71

References