Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2312454..2312717 Replicon chromosome
Accession NZ_CP014429
Organism Staphylococcus aureus strain USA300-SUR19

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag AYM32_RS12290 Protein ID WP_001802298.1
Coordinates 2312613..2312717 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 2312454..2312618 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AYM32_RS12270 2308637..2309302 - 666 WP_001024094.1 SDR family oxidoreductase -
AYM32_RS12275 2309454..2309774 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
AYM32_RS12280 2309776..2310756 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
AYM32_RS12285 2311022..2312113 + 1092 WP_000495671.1 lytic regulatory protein -
- 2312454..2312618 + 165 - - Antitoxin
AYM32_RS12290 2312613..2312717 - 105 WP_001802298.1 hypothetical protein Toxin
AYM32_RS15795 2312878..2313361 - 484 Protein_2272 recombinase family protein -
AYM32_RS12300 2313404..2314540 - 1137 WP_000115564.1 SAP domain-containing protein -
AYM32_RS12305 2314829..2314921 + 93 WP_001790138.1 hypothetical protein -
AYM32_RS12310 2315626..2316483 - 858 WP_000370924.1 Cof-type HAD-IIB family hydrolase -
AYM32_RS12315 2316551..2317333 - 783 WP_000908176.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T61135 WP_001802298.1 NZ_CP014429:c2312717-2312613 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T61135 NZ_CP014429:c2312717-2312613 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTTATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 165 bp

>AT61135 NZ_CP014429:2312454-2312618 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References