Detailed information of TA system TA061070

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1976740..1976922
• Replicon: chromosome
• Accession: NZ_CP014420
• Organism: Staphylococcus aureus strain USA300-SUR16

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: AYM29_RS15765
• Protein ID: WP_001801861.1
• Coordinates: 1976740..1976835 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1976863..1976922 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
AYM29_RS10165	1972400..1973026	+	627	Protein_1910	hypothetical protein	-
AYM29_RS10170	1973067..1973411	+	345	WP_000627551.1	DUF3969 family protein	-
AYM29_RS10175	1973509..1974060	+	552	WP_000414205.1	hypothetical protein	-
AYM29_RS10180	1974278..1974919	-	642	WP_000494956.1	ImmA/IrrE family metallo-endopeptidase	-
AYM29_RS10185	1975033..1975218	-	186	WP_000809857.1	hypothetical protein	-
AYM29_RS10190	1975220..1975396	-	177	WP_000375476.1	hypothetical protein	-
AYM29_RS10195	1975407..1975790	-	384	WP_000070811.1	hypothetical protein	-
AYM29_RS10205	1976394..1976537	-	144	WP_001549059.1	transposase	-
AYM29_RS15765	1976740..1976835	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1976863..1976922	-	60	-	-	Antitoxin
AYM29_RS10210	1976958..1977059	+	102	WP_001791893.1	hypothetical protein	-
AYM29_RS10215	1977037..1977213	-	177	Protein_1920	transposase	-
AYM29_RS10220	1977407..1977784	-	378	WP_001037045.1	DUF1433 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	lukD / hlgA	1950714..2010011	59297

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T61070 WP_001801861.1 NZ_CP014420:1976740-1976835 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T61070 NZ_CP014420:1976740-1976835 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 60 bp

>AT61070 NZ_CP014420:c1976922-1976863 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin