61025

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2312267..2312546 Replicon chromosome
Accession NZ_CP014409
Organism Staphylococcus aureus strain USA300-SUR13

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag AYM26_RS12270 Protein ID WP_001802298.1
Coordinates 2312442..2312546 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF3
Locus tag -
Coordinates 2312267..2312446 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AYM26_RS12250 2308466..2309131 - 666 WP_001024094.1 SDR family oxidoreductase -
AYM26_RS12255 2309283..2309603 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
AYM26_RS12260 2309605..2310585 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
AYM26_RS12265 2310851..2311942 + 1092 WP_000495671.1 lytic regulatory protein -
- 2312267..2312446 + 180 - - Antitoxin
AYM26_RS12270 2312442..2312546 - 105 WP_001802298.1 hypothetical protein Toxin
AYM26_RS15790 2312707..2313190 - 484 Protein_2272 recombinase family protein -
AYM26_RS12280 2313233..2314369 - 1137 WP_000115564.1 SAP domain-containing protein -
AYM26_RS12285 2314658..2314750 + 93 WP_001790138.1 hypothetical protein -
AYM26_RS12290 2315455..2316312 - 858 WP_000370924.1 Cof-type HAD-IIB family hydrolase -
AYM26_RS12295 2316380..2317162 - 783 WP_000908176.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T61025 WP_001802298.1 NZ_CP014409:c2312546-2312442 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T61025 NZ_CP014409:c2312546-2312442 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTTATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 180 bp

>AT61025 NZ_CP014409:2312267-2312446 [Staphylococcus aureus]
GTGTTAAAATATATTTGTAGTAAGTAGAAGCAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGG
AAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTC
AAAGCGAATAGAAGGTTATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References