Detailed information of TA system TA061016

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1976502..1976684
• Replicon: chromosome
• Accession: NZ_CP014409
• Organism: Staphylococcus aureus strain USA300-SUR13

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: AYM26_RS15760
• Protein ID: WP_001801861.1
• Coordinates: 1976502..1976597 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1976625..1976684 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
AYM26_RS10145	1972162..1972788	+	627	Protein_1911	hypothetical protein	-
AYM26_RS10150	1972829..1973173	+	345	WP_000627551.1	DUF3969 family protein	-
AYM26_RS10155	1973271..1973822	+	552	WP_000414205.1	hypothetical protein	-
AYM26_RS10160	1974040..1974681	-	642	WP_000494956.1	ImmA/IrrE family metallo-endopeptidase	-
AYM26_RS10165	1974795..1974980	-	186	WP_000809857.1	hypothetical protein	-
AYM26_RS10170	1974982..1975158	-	177	WP_000375476.1	hypothetical protein	-
AYM26_RS10175	1975169..1975552	-	384	WP_000070811.1	hypothetical protein	-
AYM26_RS10185	1976156..1976299	-	144	WP_001549059.1	transposase	-
AYM26_RS15760	1976502..1976597	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1976625..1976684	-	60	-	-	Antitoxin
AYM26_RS10190	1976720..1976821	+	102	WP_001791893.1	hypothetical protein	-
AYM26_RS10195	1976799..1976975	-	177	Protein_1921	transposase	-
AYM26_RS10200	1977169..1977546	-	378	WP_001037045.1	DUF1433 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	lukD / hlgA	1946137..2009773	63636

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T61016 WP_001801861.1 NZ_CP014409:1976502-1976597 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T61016 NZ_CP014409:1976502-1976597 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 60 bp

>AT61016 NZ_CP014409:c1976684-1976625 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin