Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2312282..2312545 Replicon chromosome
Accession NZ_CP014381
Organism Staphylococcus aureus strain USA300-SUR6

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag AYM19_RS12270 Protein ID WP_001802298.1
Coordinates 2312441..2312545 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 2312282..2312446 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AYM19_RS12250 2308465..2309130 - 666 WP_001024094.1 SDR family oxidoreductase -
AYM19_RS12255 2309282..2309602 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
AYM19_RS12260 2309604..2310584 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
AYM19_RS12265 2310850..2311941 + 1092 WP_000495671.1 lytic regulatory protein -
- 2312282..2312446 + 165 - - Antitoxin
AYM19_RS12270 2312441..2312545 - 105 WP_001802298.1 hypothetical protein Toxin
AYM19_RS15660 2312706..2313189 - 484 Protein_2272 recombinase family protein -
AYM19_RS12280 2313232..2314368 - 1137 WP_000115564.1 SAP domain-containing protein -
AYM19_RS12285 2314657..2314749 + 93 WP_001790138.1 hypothetical protein -
AYM19_RS12290 2315454..2316311 - 858 WP_000370924.1 Cof-type HAD-IIB family hydrolase -
AYM19_RS12295 2316379..2317161 - 783 WP_000908176.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T60903 WP_001802298.1 NZ_CP014381:c2312545-2312441 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T60903 NZ_CP014381:c2312545-2312441 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTTATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 165 bp

>AT60903 NZ_CP014381:2312282-2312446 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References