Detailed information of TA system TA060838

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1976490..1976672
• Replicon: chromosome
• Accession: NZ_CP014368
• Organism: Staphylococcus aureus strain USA300-SUR3

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: AYM15_RS10170
• Protein ID: WP_001801861.1
• Coordinates: 1976490..1976585 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1976613..1976672 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
AYM15_RS10120	1972150..1972776	+	627	Protein_1911	hypothetical protein	-
AYM15_RS10125	1972817..1973161	+	345	WP_000627551.1	DUF3969 family protein	-
AYM15_RS10130	1973259..1973810	+	552	WP_000414205.1	hypothetical protein	-
AYM15_RS10135	1974028..1974669	-	642	WP_000494956.1	ImmA/IrrE family metallo-endopeptidase	-
AYM15_RS10140	1974783..1974968	-	186	WP_000809857.1	hypothetical protein	-
AYM15_RS10145	1974970..1975146	-	177	WP_000375476.1	hypothetical protein	-
AYM15_RS10150	1975157..1975540	-	384	WP_000070811.1	hypothetical protein	-
AYM15_RS10160	1976144..1976287	-	144	WP_001549059.1	transposase	-
AYM15_RS10170	1976490..1976585	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1976613..1976672	-	60	-	-	Antitoxin
AYM15_RS10175	1976708..1976809	+	102	WP_001791893.1	hypothetical protein	-
AYM15_RS10180	1976787..1976963	-	177	Protein_1921	transposase	-
AYM15_RS10185	1977157..1977534	-	378	WP_001037045.1	DUF1433 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	lukD / hlgA	1950464..2009761	59297

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T60838 WP_001801861.1 NZ_CP014368:1976490-1976585 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T60838 NZ_CP014368:1976490-1976585 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 60 bp

>AT60838 NZ_CP014368:c1976672-1976613 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin