Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2297519..2297782 Replicon chromosome
Accession NZ_CP014365
Organism Staphylococcus aureus strain USA300-SUR2

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag AYM14_RS12205 Protein ID WP_001802298.1
Coordinates 2297678..2297782 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 2297519..2297683 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AYM14_RS12185 2293702..2294367 - 666 WP_001024094.1 SDR family oxidoreductase -
AYM14_RS12190 2294519..2294839 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
AYM14_RS12195 2294841..2295821 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
AYM14_RS12200 2296087..2297178 + 1092 WP_000495671.1 lytic regulatory protein -
- 2297519..2297683 + 165 - - Antitoxin
AYM14_RS12205 2297678..2297782 - 105 WP_001802298.1 hypothetical protein Toxin
AYM14_RS15595 2297943..2298426 - 484 Protein_2259 recombinase family protein -
AYM14_RS12215 2298469..2299605 - 1137 WP_000115564.1 SAP domain-containing protein -
AYM14_RS12220 2299894..2299986 + 93 WP_001790138.1 hypothetical protein -
AYM14_RS12225 2300691..2301548 - 858 WP_000370924.1 Cof-type HAD-IIB family hydrolase -
AYM14_RS12230 2301616..2302398 - 783 WP_000908176.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T60831 WP_001802298.1 NZ_CP014365:c2297782-2297678 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T60831 NZ_CP014365:c2297782-2297678 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTTATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 165 bp

>AT60831 NZ_CP014365:2297519-2297683 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References