60597

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) ldrD-rdlD/Ldr(toxin)
Location 3802789..3803011 Replicon chromosome
Accession NZ_CP014272
Organism Escherichia coli K-12 strain K-12 C3026

Toxin (Protein)


Gene name ldrD Uniprot ID S1E8T8
Locus tag C3026_RS19145 Protein ID WP_000141634.1
Coordinates 3802789..3802896 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name rdlD
Locus tag -
Coordinates 3802945..3803011 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C3026_RS19120 3798042..3798794 - 753 Protein_3686 cellulose biosynthesis protein BcsQ -
C3026_RS19125 3798806..3798994 - 189 WP_001063318.1 YhjR family protein -
C3026_RS19130 3799267..3800838 + 1572 WP_001204927.1 cellulose biosynthesis protein BcsE -
C3026_RS19135 3800835..3801026 + 192 WP_000988308.1 cellulose biosynthesis protein BcsF -
C3026_RS19140 3801023..3802702 + 1680 WP_000191622.1 cellulose biosynthesis protein BcsG -
C3026_RS19145 3802789..3802896 - 108 WP_000141634.1 type I toxin-antitoxin system toxic polypeptide LdrD Toxin
- 3802945..3803011 + 67 - - Antitoxin
C3026_RS19155 3803372..3804643 + 1272 WP_001295225.1 transporter -
C3026_RS19160 3804673..3805677 - 1005 WP_000107012.1 dipeptide ABC transporter ATP-binding subunit DppF -
C3026_RS19165 3805674..3806657 - 984 WP_001196486.1 dipeptide ABC transporter ATP-binding protein -
C3026_RS19170 3806668..3807570 - 903 WP_000084677.1 dipeptide ABC transporter permease DppC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 3916.72 Da        Isoelectric Point: 9.0157

>T60597 WP_000141634.1 NZ_CP014272:c3802896-3802789 [Escherichia coli K-12]
MTFAELGMAFWHDLAAPVIAGILASMIVNWLNKRK

Download         Length: 108 bp

>T60597 NZ_CP014272:c3802896-3802789 [Escherichia coli K-12]
ATGACGTTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin


Download         Length: 67 bp

>AT60597 NZ_CP014272:3802945-3803011 [Escherichia coli K-12]
GTCTAGAGTCAAGATTAGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
PDB 5LBJ

Antitoxin

Download structure file

References