Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) ldrD-rdlD/Ldr(toxin)
Location 1897180..1897402 Replicon chromosome
Accession NZ_CP014225
Organism Escherichia coli str. K-12 substr. MG1655 strain K-12

Toxin (Protein)


Gene name ldrD Uniprot ID S1E8T8
Locus tag AW869_RS09365 Protein ID WP_000141634.1
Coordinates 1897180..1897287 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name rdlD
Locus tag -
Coordinates 1897336..1897402 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AW869_RS09340 1892433..1893185 - 753 Protein_1782 cellulose biosynthesis protein BcsQ -
AW869_RS09345 1893197..1893385 - 189 WP_001063318.1 YhjR family protein -
AW869_RS09350 1893658..1895229 + 1572 WP_001204931.1 cellulose biosynthesis protein BcsE -
AW869_RS09355 1895226..1895417 + 192 WP_000988308.1 cellulose biosynthesis protein BcsF -
AW869_RS09360 1895414..1897093 + 1680 WP_000191622.1 cellulose biosynthesis protein BcsG -
AW869_RS09365 1897180..1897287 - 108 WP_000141634.1 type I toxin-antitoxin system toxic polypeptide LdrD Toxin
- 1897336..1897402 + 67 - - Antitoxin
AW869_RS09375 1897763..1899034 + 1272 WP_001295225.1 transporter -
AW869_RS09380 1899064..1900068 - 1005 WP_000107012.1 dipeptide ABC transporter ATP-binding subunit DppF -
AW869_RS09385 1900065..1901048 - 984 WP_001196486.1 dipeptide ABC transporter ATP-binding protein -
AW869_RS09390 1901059..1901961 - 903 WP_000084677.1 dipeptide ABC transporter permease DppC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 3916.72 Da        Isoelectric Point: 9.0157

>T60389 WP_000141634.1 NZ_CP014225:c1897287-1897180 [Escherichia coli str. K-12 substr. MG1655]
MTFAELGMAFWHDLAAPVIAGILASMIVNWLNKRK

Download         Length: 108 bp

>T60389 NZ_CP014225:c1897287-1897180 [Escherichia coli str. K-12 substr. MG1655]
ATGACGTTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin


Download         Length: 67 bp

>AT60389 NZ_CP014225:1897336-1897402 [Escherichia coli str. K-12 substr. MG1655]
GTCTAGAGTCAAGATTAGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
PDB 5LBJ

Antitoxin

Download structure file

References