Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yafN-yafO (relBE)/YafO-YafN
Location 284888..285582 Replicon chromosome
Accession NZ_CP014137
Organism Brenneria goodwinii strain FRB141

Toxin (Protein)


Gene name yafO Uniprot ID -
Locus tag AWC36_RS01310 Protein ID WP_183096850.1
Coordinates 285184..285582 (+) Length 133 a.a.

Antitoxin (Protein)


Gene name yafN Uniprot ID -
Locus tag AWC36_RS01305 Protein ID WP_095833361.1
Coordinates 284888..285181 (+) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AWC36_RS01295 280385..281581 + 1197 WP_095833360.1 hypothetical protein -
AWC36_RS24220 281873..282043 - 171 WP_183096849.1 hypothetical protein -
AWC36_RS01300 282513..284495 + 1983 WP_183096848.1 hypothetical protein -
AWC36_RS01305 284888..285181 + 294 WP_095833361.1 type I toxin-antitoxin system antitoxin YafN Antitoxin
AWC36_RS01310 285184..285582 + 399 WP_183096850.1 type II toxin-antitoxin system YafO family toxin Toxin
AWC36_RS01315 286189..287720 + 1532 WP_095833363.1 IS3 family transposase -
AWC36_RS01320 288061..288765 - 705 WP_095833364.1 hypothetical protein -
AWC36_RS01325 288972..289487 - 516 WP_048639824.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 250011..293153 43142


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin YafO

(27-130)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 133 a.a.        Molecular weight: 15276.54 Da        Isoelectric Point: 7.0608

>T60247 WP_183096850.1 NZ_CP014137:285184-285582 [Brenneria goodwinii]
IRIFKSALIRQQLSQQELDDLAADFLSYKKDGVLPDTFGRDAPYDDDRTYPLVKEEQVAHIHLADADAPFPKFLRQFKRT
SDQAHLVYCQGAMDPDAYLLIIILKPEAHKMARNNNYMHKIGMIAEAFRMKH

Download         Length: 399 bp

>T60247 NZ_CP014137:285184-285582 [Brenneria goodwinii]
ATTAGGATTTTCAAGTCAGCACTGATTCGCCAGCAATTGAGCCAGCAAGAGCTTGATGATTTGGCGGCGGATTTTCTGTC
CTACAAAAAAGACGGCGTGTTGCCAGATACCTTTGGTCGTGATGCACCCTATGATGATGACCGCACCTATCCCTTGGTAA
AAGAAGAGCAGGTAGCTCACATTCATCTTGCCGATGCGGATGCCCCTTTCCCTAAGTTTTTACGTCAGTTCAAACGAACC
AGCGATCAGGCGCATTTGGTATACTGCCAAGGTGCGATGGATCCCGATGCTTATCTGCTGATTATCATCCTGAAACCCGA
AGCGCATAAAATGGCGCGAAACAATAACTATATGCATAAGATCGGGATGATAGCCGAAGCATTCAGGATGAAGCATTAA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 11007.49 Da        Isoelectric Point: 4.9167

>AT60247 WP_095833361.1 NZ_CP014137:284888-285181 [Brenneria goodwinii]
MERILAEKSINITELRKNPAKYFIDEPVAVLSNNRPAGYMVSAKVFEELIDLLEEKQGRIHTAARFRPTAERLSDIADSG
QKLLQNASDKDLTEFTE

Download         Length: 294 bp

>AT60247 NZ_CP014137:284888-285181 [Brenneria goodwinii]
ATGGAACGCATCCTCGCAGAAAAATCTATCAACATCACTGAGTTAAGAAAAAATCCGGCAAAATACTTCATTGATGAGCC
TGTTGCTGTTCTGTCTAATAATCGTCCTGCTGGTTACATGGTCAGTGCCAAGGTGTTTGAAGAGCTGATCGATCTGTTAG
AAGAGAAGCAGGGCAGGATTCATACCGCTGCGCGTTTCAGGCCAACGGCTGAGCGTTTAAGTGATATTGCGGATAGTGGG
CAGAAACTGCTGCAAAACGCCTCTGACAAGGATCTGACCGAGTTCACGGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References