Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 484158..484315 Replicon chromosome
Accession NZ_CP014113
Organism Staphylococcus saprophyticus strain FDAARGOS_168

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag AL528_RS13135 Protein ID WP_002441941.1
Coordinates 484220..484315 (-) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 484158..484191 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AL528_RS02415 479945..480778 + 834 WP_048787569.1 aldo/keto reductase -
AL528_RS02420 481245..481544 - 300 WP_011304021.1 hypothetical protein -
AL528_RS02425 481921..482154 + 234 WP_048787568.1 ferrous iron transport protein A -
AL528_RS13130 482215..482280 - 66 WP_162009580.1 type I toxin-antitoxin system Fst family toxin -
AL528_RS02430 482468..483862 - 1395 WP_048787567.1 RES family NAD+ phosphorylase -
- 484158..484191 + 34 - - Antitoxin
AL528_RS13135 484220..484315 - 96 WP_002441941.1 type I toxin-antitoxin system Fst family toxin Toxin
AL528_RS02435 484618..485376 - 759 WP_011304024.1 MerR family transcriptional regulator -
AL528_RS02440 485486..486049 - 564 WP_048787566.1 helix-turn-helix domain-containing protein -
AL528_RS02445 486243..487700 - 1458 WP_011304026.1 carbon starvation protein A -
AL528_RS02450 487908..488747 - 840 WP_002481957.1 ParB/RepB/Spo0J family partition protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3560.34 Da        Isoelectric Point: 9.9256

>T60184 WP_002441941.1 NZ_CP014113:c484315-484220 [Staphylococcus saprophyticus]
MLMIFVHIIAPVISGCAVAYFTYWLSSKRNK

Download         Length: 96 bp

>T60184 NZ_CP014113:c484315-484220 [Staphylococcus saprophyticus]
ATGCTTATGATCTTCGTTCACATCATTGCACCAGTCATTAGTGGCTGTGCAGTTGCGTATTTTACTTATTGGCTTAGTAG
TAAACGCAATAAATAG

Antitoxin


Download         Length: 34 bp

>AT60184 NZ_CP014113:484158-484191 [Staphylococcus saprophyticus]
CACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References