Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) ldrD-rdlD/Ldr(toxin)
Location 3102770..3102992 Replicon chromosome
Accession NZ_CP014111
Organism Escherichia coli strain FDAARGOS_144

Toxin (Protein)


Gene name ldrD Uniprot ID S1NWX0
Locus tag AL502_RS26335 Protein ID WP_001295224.1
Coordinates 3102770..3102877 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name rdlD
Locus tag -
Coordinates 3102934..3102992 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AL502_RS16945 3097822..3098010 - 189 WP_001063314.1 YhjR family protein -
AL502_RS16950 3098283..3099854 + 1572 WP_001204941.1 cellulose biosynthesis protein BcsE -
AL502_RS16955 3099851..3100042 + 192 WP_000988308.1 cellulose biosynthesis protein BcsF -
AL502_RS16960 3100039..3101718 + 1680 WP_022296260.1 cellulose biosynthesis protein BcsG -
AL502_RS16965 3101804..3101911 - 108 WP_001295224.1 type I toxin-antitoxin system toxin Ldr family protein -
AL502_RS26330 3102287..3102394 - 108 WP_000170748.1 type I toxin-antitoxin system toxin Ldr family protein -
AL502_RS26335 3102770..3102877 - 108 WP_001295224.1 type I toxin-antitoxin system toxin Ldr family protein Toxin
- 3102934..3102992 + 59 - - Antitoxin
AL502_RS16990 3103353..3104624 + 1272 WP_001296513.1 amino acid permease -
AL502_RS16995 3104654..3105658 - 1005 WP_000103571.1 dipeptide ABC transporter ATP-binding subunit DppF -
AL502_RS17000 3105655..3106638 - 984 WP_001196477.1 dipeptide ABC transporter ATP-binding protein -
AL502_RS17005 3106649..3107551 - 903 WP_000084677.1 dipeptide ABC transporter permease DppC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 3882.70 Da        Isoelectric Point: 9.0157

>T60166 WP_001295224.1 NZ_CP014111:c3102877-3102770 [Escherichia coli]
MTLAELGMAFWHDLAAPVIAGILASMIVNWLNKRK

Download         Length: 108 bp

>T60166 NZ_CP014111:c3102877-3102770 [Escherichia coli]
ATGACGCTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin


Download         Length: 59 bp

>AT60166 NZ_CP014111:3102934-3102992 [Escherichia coli]
TCAAGATTAGCCCCCGTGATGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A4P7TSJ7

Antitoxin

Download structure file

References