Detailed information of TA system TA060083

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 57491..57755
• Replicon: plasmid unnamed
• Accession: NZ_CP014068
• Organism: Enterococcus gallinarum strain FDAARGOS_163

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: AL523_RS18115
• Protein ID: WP_082741618.1
• Coordinates: 57491..57634 (+)
• Length: 48 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	57616..57755 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
AL523_RS18065	52685..52987	-	303	WP_061054561.1	hypothetical protein	-
AL523_RS18070	53068..53829	-	762	WP_082741617.1	N-6 DNA methylase	-
AL523_RS18075	53878..54117	-	240	WP_016612842.1	hypothetical protein	-
AL523_RS18080	54184..54510	-	327	WP_061054563.1	hypothetical protein	-
AL523_RS18090	55048..55536	-	489	WP_061054565.1	single-stranded DNA-binding protein	-
AL523_RS18095	55567..55746	-	180	WP_016620941.1	hypothetical protein	-
AL523_RS18100	55746..56024	-	279	WP_061054566.1	hypothetical protein	-
AL523_RS18475	56103..56246	-	144	WP_167389037.1	hypothetical protein	-
AL523_RS18105	56276..56800	-	525	WP_061054567.1	hypothetical protein	-
AL523_RS18115	57491..57634	+	144	WP_082741618.1	putative holin-like toxin	Toxin
-	57616..57755	-	140	NuclAT_0	-	Antitoxin
AL523_RS18120	57937..58749	-	813	WP_104010409.1	replication-relaxation family protein	-
AL523_RS18125	59487..61661	-	2175	WP_061054569.1	TraM recognition domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..88126	88126

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (14-47)

Sequences

Toxin

Protein

• Length: 48 a.a.
• Molecular weight: 5387.51 Da
• Isoelectric Point: 10.7385

>T60083 WP_082741618.1 NZ_CP014068:57491-57634 [Enterococcus gallinarum]
MSVLPTSYERRRLLSAYETIQTILGFGMFTIALISLVVKLLKNDKKK

Nucleotide

• Length: 144 bp

>T60083 NZ_CP014068:57491-57634 [Enterococcus gallinarum]
ATGAGCGTACTTCCAACATCTTATGAAAGGAGACGCCTTTTGTCTGCATACGAAACAATTCAGACCATCCTTGGCTTTGG
TATGTTTACCATTGCTTTGATCAGTCTGGTTGTCAAGTTGCTTAAAAACGACAAAAAGAAATAA

Antitoxin

Nucleotide

• Length: 140 bp

>AT60083 NZ_CP014068:c57755-57616 [Enterococcus gallinarum]
TGGTATAATAAGTATGTAAAGAGGAGTTGCTTCAACAACTCCCCTTGGACAGCACCGTTAAAGACGGTGACAGAAATTTA
ATTATCTAAAAAGAGATAACCGACTCCTGCTAAAGTGACGGTTATTTCTTTTTGTCGTTT

Structures

Antitoxin