Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1051727..1051907 Replicon chromosome
Accession NZ_CP014064
Organism Staphylococcus aureus strain FDAARGOS_159

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag AL519_RS14815 Protein ID WP_001801861.1
Coordinates 1051727..1051822 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1051850..1051907 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AL519_RS05540 1046890..1047540 + 651 WP_001795210.1 excalibur calcium-binding domain-containing protein -
AL519_RS05545 1047621..1048616 + 996 WP_000070642.1 DUF4352 domain-containing protein -
AL519_RS05550 1048691..1049317 + 627 WP_000669024.1 hypothetical protein -
AL519_RS05555 1049358..1049699 + 342 WP_000627540.1 DUF3969 family protein -
AL519_RS05560 1049800..1050372 + 573 WP_061047279.1 hypothetical protein -
AL519_RS05565 1050570..1051582 - 1013 Protein_1022 IS3 family transposase -
AL519_RS14815 1051727..1051822 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1051850..1051907 - 58 - - Antitoxin
AL519_RS05570 1051945..1052046 + 102 WP_001792025.1 hypothetical protein -
AL519_RS05575 1052024..1052185 - 162 Protein_1025 transposase -
AL519_RS05580 1052176..1052670 - 495 Protein_1026 transposase -
AL519_RS05585 1053122..1054351 - 1230 WP_000072627.1 restriction endonuclease subunit S -
AL519_RS05590 1054344..1055900 - 1557 WP_000028669.1 type I restriction-modification system subunit M -
AL519_RS05595 1056064..1056198 - 135 WP_001791797.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - lukD / hlgA / selk 1046132..1097985 51853


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T60063 WP_001801861.1 NZ_CP014064:1051727-1051822 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T60063 NZ_CP014064:1051727-1051822 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 58 bp

>AT60063 NZ_CP014064:c1051907-1051850 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References