Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1669..1826 Replicon chromosome
Accession NZ_CP014057
Organism Staphylococcus saprophyticus strain FDAARGOS_137

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag AL494_RS12705 Protein ID WP_002441941.1
Coordinates 1731..1826 (-) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1669..1702 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AL494_RS00005 3..1373 - 1371 Protein_0 RES family NAD+ phosphorylase -
- 1669..1702 + 34 - - Antitoxin
AL494_RS12705 1731..1826 - 96 WP_002441941.1 type I toxin-antitoxin system Fst family toxin Toxin
AL494_RS00010 2129..2887 - 759 WP_011304024.1 MerR family transcriptional regulator -
AL494_RS00015 2997..3560 - 564 WP_048787566.1 helix-turn-helix domain-containing protein -
AL494_RS00020 3754..5211 - 1458 WP_061046304.1 carbon starvation protein A -
AL494_RS00025 5419..6258 - 840 WP_002481957.1 ParB/RepB/Spo0J family partition protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.



Sequences


Toxin        


Download         Length: 32 a.a.        Molecular weight: 3560.34 Da        Isoelectric Point: 9.9256

>T60047 WP_002441941.1 NZ_CP014057:c1826-1731 [Staphylococcus saprophyticus]
MLMIFVHIIAPVISGCAVAYFTYWLSSKRNK

Download         Length: 96 bp

>T60047 NZ_CP014057:c1826-1731 [Staphylococcus saprophyticus]
ATGCTTATGATCTTCGTTCACATCATTGCACCAGTCATTAGTGGCTGTGCAGTTGCGTATTTTACTTATTGGCTTAGTAG
TAAACGCAATAAATAG

Antitoxin


Download         Length: 34 bp

>AT60047 NZ_CP014057:1669-1702 [Staphylococcus saprophyticus]
CACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Download structure file

References