Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 1141990..1142686 Replicon chromosome
Accession NZ_CP014031
Organism Hafnia paralvei strain FDAARGOS_158

Toxin (Protein)


Gene name mqsR Uniprot ID -
Locus tag AL518_RS05300 Protein ID WP_061059394.1
Coordinates 1141990..1142301 (+) Length 104 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID -
Locus tag AL518_RS05305 Protein ID WP_061059395.1
Coordinates 1142288..1142686 (+) Length 133 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AL518_RS05265 1137432..1138175 + 744 WP_008815656.1 glycerophosphodiester phosphodiesterase -
AL518_RS05280 1138922..1139356 - 435 WP_061059393.1 hypothetical protein -
AL518_RS05285 1139630..1139959 + 330 WP_008815654.1 thiosulfate sulfurtransferase GlpE -
AL518_RS05290 1140112..1140948 + 837 WP_008815653.1 rhomboid family intramembrane serine protease GlpG -
AL518_RS05295 1140982..1141740 + 759 WP_004096965.1 DeoR/GlpR family transcriptional regulator -
AL518_RS05300 1141990..1142301 + 312 WP_061059394.1 type II toxin-antitoxin system MqsR family toxin Toxin
AL518_RS05305 1142288..1142686 + 399 WP_061059395.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
AL518_RS05310 1142929..1144416 + 1488 WP_061059396.1 glycerol-3-phosphate dehydrogenase -
AL518_RS05315 1144498..1144785 - 288 WP_008815650.1 transcriptional regulator -
AL518_RS05320 1145113..1145955 - 843 WP_061059397.1 AraC family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(5-97)

Antitoxin

Zinc finger, MqsA-type

(3-44)


Sequences

Toxin        


Download         Length: 104 a.a.        Molecular weight: 12084.95 Da        Isoelectric Point: 9.5189

>T59980 WP_061059394.1 NZ_CP014031:1141990-1142301 [Hafnia paralvei]
MEKRTPHCRLEKIRSLIGKGLIRATALSSRNARQLNFSRADMYRIVSELSTQGFHKSMTTYENHRVWQDVYHCHLDKVSL
YLKLTVIDEVLIVSFKELNDDMS

Download         Length: 312 bp

>T59980 NZ_CP014031:1141990-1142301 [Hafnia paralvei]
ATGGAAAAGCGAACACCGCATTGCCGATTAGAAAAGATACGGAGTCTGATAGGGAAGGGGTTGATTAGAGCAACAGCATT
GTCGTCTCGGAACGCAAGACAGCTAAATTTTAGTCGTGCTGATATGTATCGAATAGTGAGCGAATTGTCTACGCAGGGCT
TTCATAAAAGTATGACGACCTATGAGAACCACCGAGTTTGGCAAGATGTTTACCACTGCCATCTGGATAAAGTGTCTCTC
TATCTGAAGTTAACGGTAATTGATGAAGTGTTGATCGTTTCTTTTAAGGAGCTGAATGATGATATGTCCTGA

Antitoxin


Download         Length: 133 a.a.        Molecular weight: 14667.94 Da        Isoelectric Point: 4.9471

>AT59980 WP_061059395.1 NZ_CP014031:1142288-1142686 [Hafnia paralvei]
MICPECGSVNTVKEYRDMPYTYKGQTIIVKAVGADWCLNCGEGVVFTEESIRIDSIMGDFNKQVNASIIEPEFVIAMRKK
LNLSQSEAGEIFGGGVNAFSRYETGKALPHVSTIKLLKLLDKYPELLAEIRD

Download         Length: 399 bp

>AT59980 NZ_CP014031:1142288-1142686 [Hafnia paralvei]
ATGATATGTCCTGAATGTGGCTCAGTGAATACGGTAAAGGAATACCGTGATATGCCTTATACCTACAAAGGTCAGACGAT
AATCGTTAAGGCTGTTGGCGCTGATTGGTGTCTCAACTGTGGGGAGGGTGTTGTTTTCACTGAGGAGTCAATTCGTATTG
ATAGCATCATGGGAGATTTTAACAAACAGGTAAATGCCTCTATCATTGAACCTGAATTCGTTATCGCGATGCGAAAAAAG
CTTAATCTGTCTCAAAGTGAGGCCGGTGAGATCTTTGGCGGTGGGGTCAACGCCTTCTCACGCTATGAGACAGGCAAGGC
TCTTCCCCATGTTTCCACCATCAAACTGCTAAAGCTGTTAGATAAATATCCCGAACTGCTCGCCGAAATCCGCGATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References