Detailed information of TA system TA059745

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 1720525..1720784
• Replicon: chromosome
• Accession: NZ_CP013980
• Organism: Staphylococcus equorum strain KM1031

Toxin (Protein)

• Gene name: SprG2
• Uniprot ID: -
• Locus tag: AWC34_RS13380
• Protein ID: WP_002511402.1
• Coordinates: 1720677..1720784 (-)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprF1
Locus tag	-
Coordinates	1720525..1720687 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
AWC34_RS08260	1716128..1717165	-	1038	WP_021339833.1	lactonase family protein	-
AWC34_RS08265	1717342..1717752	+	411	WP_002507169.1	YolD-like family protein	-
AWC34_RS13570	1718206..1718376	-	171	WP_002507168.1	hypothetical protein	-
AWC34_RS08270	1718871..1719911	+	1041	WP_021339984.1	choloylglycine hydrolase	-
AWC34_RS13575	1720219..1720389	+	171	WP_021339983.1	tyrosine-type recombinase/integrase	-
-	1720525..1720687	+	163	-	-	Antitoxin
AWC34_RS13380	1720677..1720784	-	108	WP_002511402.1	putative holin-like toxin	Toxin
AWC34_RS08275	1721150..1722001	-	852	WP_021339982.1	DUF4097 family beta strand repeat protein	-
AWC34_RS08280	1721998..1722558	-	561	WP_002511403.1	DUF1700 domain-containing protein	-
AWC34_RS08285	1722653..1723138	-	486	WP_021339981.1	hypothetical protein	-
AWC34_RS08290	1723309..1723869	+	561	WP_002507158.1	thioredoxin family protein	-
AWC34_RS08295	1723952..1724680	-	729	WP_002507157.1	ABC transporter permease subunit	-
AWC34_RS08300	1724680..1725552	-	873	WP_002507156.1	ABC transporter ATP-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (4-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3756.72 Da
• Isoelectric Point: 10.4997

>T59745 WP_002511402.1 NZ_CP013980:c1720784-1720677 [Staphylococcus equorum]
VVPIVEALHLMLGFGTFIVTLLGLVVAIVKLSHKK

Nucleotide

• Length: 108 bp

>T59745 NZ_CP013980:c1720784-1720677 [Staphylococcus equorum]
GTGGTTCCAATTGTAGAAGCACTACACTTAATGTTAGGTTTCGGTACTTTCATCGTTACCTTATTAGGTTTAGTGGTTGC
AATTGTTAAATTAAGCCATAAAAAATAA

Antitoxin

Nucleotide

• Length: 163 bp

>AT59745 NZ_CP013980:1720525-1720687 [Staphylococcus equorum]
ATTTGATAATATTTTTATGTTGTGGTAATTTATATATAGAAAAAGGGCAACACACCATAAGTGTATCGCCCTAATGAGCC
CGTTAAAAAGACGGTGGCTGGAATTTAATAATGATTAAATAATCATCTCATCCTCGCCAAAGTTAGAGATGGTTATTTTT
TAT

Structures

Antitoxin