Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2750570..2750754 Replicon chromosome
Accession NZ_CP013957
Organism Staphylococcus aureus strain V521 isolate Sequencing

Toxin (Protein)


Gene name SprA2 Uniprot ID Q2FVI9
Locus tag ASL17_RS14345 Protein ID WP_000482650.1
Coordinates 2750647..2750754 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2750570..2750630 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ASL17_RS14320 2746100..2746267 - 168 WP_001790576.1 hypothetical protein -
ASL17_RS14330 2746498..2748231 - 1734 WP_000486494.1 ABC transporter ATP-binding protein/permease -
ASL17_RS14335 2748256..2750019 - 1764 WP_001064838.1 ABC transporter ATP-binding protein/permease -
- 2750570..2750630 + 61 - - Antitoxin
ASL17_RS14345 2750647..2750754 - 108 WP_000482650.1 type I toxin-antitoxin system Fst family toxin Toxin
ASL17_RS14350 2750888..2751274 - 387 WP_000779358.1 flippase GtxA -
ASL17_RS14355 2751542..2752684 + 1143 WP_001176863.1 glycerate kinase -
ASL17_RS14360 2752744..2753403 + 660 WP_063655758.1 hypothetical protein -
ASL17_RS14365 2753585..2754796 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
ASL17_RS14370 2754919..2755392 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4011.78 Da        Isoelectric Point: 11.0582

>T59727 WP_000482650.1 NZ_CP013957:c2750754-2750647 [Staphylococcus aureus]
MFNLLINIMTSAISGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T59727 NZ_CP013957:c2750754-2750647 [Staphylococcus aureus]
ATGTTCAATTTATTAATTAACATCATGACTTCAGCTATAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT59727 NZ_CP013957:2750570-2750630 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2C9TTS8

Antitoxin

Download structure file

References