Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2460139..2460418 Replicon chromosome
Accession NZ_CP013957
Organism Staphylococcus aureus strain V521 isolate Sequencing

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag ASL17_RS12770 Protein ID WP_001802298.1
Coordinates 2460314..2460418 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF3
Locus tag -
Coordinates 2460139..2460318 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ASL17_RS12750 2456338..2457003 - 666 WP_001024094.1 SDR family oxidoreductase -
ASL17_RS12755 2457155..2457475 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
ASL17_RS12760 2457477..2458457 + 981 WP_063655743.1 CDF family zinc efflux transporter CzrB -
ASL17_RS12765 2458723..2459814 + 1092 WP_000495671.1 lytic regulatory protein -
- 2460139..2460318 + 180 - - Antitoxin
ASL17_RS12770 2460314..2460418 - 105 WP_001802298.1 hypothetical protein Toxin
ASL17_RS17085 2460579..2461062 - 484 Protein_2445 recombinase family protein -
ASL17_RS12780 2461105..2462241 - 1137 WP_000115564.1 SAP domain-containing protein -
ASL17_RS12785 2462530..2462622 + 93 WP_001790138.1 hypothetical protein -
ASL17_RS12790 2463327..2464184 - 858 WP_000370924.1 Cof-type HAD-IIB family hydrolase -
ASL17_RS12795 2464252..2465034 - 783 WP_000908176.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T59722 WP_001802298.1 NZ_CP013957:c2460418-2460314 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T59722 NZ_CP013957:c2460418-2460314 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTTATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 180 bp

>AT59722 NZ_CP013957:2460139-2460318 [Staphylococcus aureus]
GTGTTAAAATATATTTGTAGTAAGTAGAAGCAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGG
AAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTC
AAAGCGAATAGAAGGTTATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References