Detailed information of TA system TA059698

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 2000999..2001179
• Replicon: chromosome
• Accession: NZ_CP013955
• Organism: Staphylococcus aureus strain NCCP14562 isolate Sequencing

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: ASL15_RS15725
• Protein ID: WP_001801861.1
• Coordinates: 2000999..2001094 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	2001122..2001179 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ASL15_RS09860	1996162..1996812	+	651	WP_001795210.1	excalibur calcium-binding domain-containing protein	-
ASL15_RS09865	1996893..1997888	+	996	WP_000070642.1	DUF4352 domain-containing protein	-
ASL15_RS09870	1997963..1998589	+	627	WP_000669024.1	hypothetical protein	-
ASL15_RS09875	1998630..1998971	+	342	WP_000627540.1	DUF3969 family protein	-
ASL15_RS09880	1999072..1999644	+	573	WP_000414216.1	hypothetical protein	-
ASL15_RS15310	1999842..2000854	-	1013	Protein_1914	IS3 family transposase	-
ASL15_RS15725	2000999..2001094	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	2001122..2001179	-	58	-	-	Antitoxin
ASL15_RS09900	2001217..2001318	+	102	WP_001792025.1	hypothetical protein	-
ASL15_RS15730	2001296..2001457	-	162	Protein_1917	transposase	-
ASL15_RS09905	2001448..2001942	-	495	Protein_1918	transposase	-
ASL15_RS09910	2002394..2003623	-	1230	WP_000072627.1	restriction endonuclease subunit S	-
ASL15_RS09915	2003616..2005172	-	1557	WP_000028669.1	type I restriction-modification system subunit M	-
ASL15_RS09920	2005336..2005470	-	135	WP_001791797.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	lukD / hlgA / selk	1995404..2048745	53341

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T59698 WP_001801861.1 NZ_CP013955:2000999-2001094 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T59698 NZ_CP013955:2000999-2001094 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 58 bp

>AT59698 NZ_CP013955:c2001179-2001122 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin