Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2347105..2347367 Replicon chromosome
Accession NZ_CP013953
Organism Staphylococcus aureus strain NCCP14558 isolate sequencing

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag ASL16_RS12000 Protein ID WP_001802298.1
Coordinates 2347263..2347367 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF2
Locus tag -
Coordinates 2347105..2347268 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ASL16_RS11980 2343357..2344022 - 666 WP_001024095.1 SDR family oxidoreductase -
ASL16_RS11985 2344174..2344494 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
ASL16_RS11990 2344496..2345473 + 978 WP_000019734.1 CDF family zinc efflux transporter CzrB -
ASL16_RS11995 2345739..2346830 + 1092 WP_000495669.1 hypothetical protein -
- 2347105..2347268 + 164 - - Antitoxin
ASL16_RS12000 2347263..2347367 - 105 WP_001802298.1 hypothetical protein Toxin
ASL16_RS15730 2348047..2348205 + 159 WP_001792784.1 hypothetical protein -
ASL16_RS12005 2348863..2349720 - 858 WP_063663594.1 Cof-type HAD-IIB family hydrolase -
ASL16_RS12010 2349788..2350570 - 783 WP_000908182.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T59688 WP_001802298.1 NZ_CP013953:c2347367-2347263 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T59688 NZ_CP013953:c2347367-2347263 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 164 bp

>AT59688 NZ_CP013953:2347105-2347268 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCAAAGCGAATAGAAGGTT
ATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References