Detailed information of TA system TA059578

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 680453..680714
• Replicon: chromosome
• Accession: NZ_CP013922
• Organism: Staphylococcus xylosus strain S170

Toxin (Protein)

• Gene name: SprG2
• Uniprot ID: -
• Locus tag: AWC37_RS03340
• Protein ID: WP_081224963.1
• Coordinates: 680453..680560 (+)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprF1
Locus tag	-
Coordinates	680550..680714 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
AWC37_RS03320	676214..676546	+	333	WP_081224960.1	DUF2977 domain-containing protein	-
AWC37_RS03325	676603..678489	+	1887	WP_081224961.1	glucosaminidase domain-containing protein	-
AWC37_RS03330	678524..678811	+	288	WP_081224962.1	hypothetical protein	-
AWC37_RS13965	679199..680317	+	1119	WP_182475319.1	hypothetical protein	-
AWC37_RS03340	680453..680560	+	108	WP_081224963.1	putative holin-like toxin	Toxin
-	680550..680714	-	165	-	-	Antitoxin
AWC37_RS03345	680765..681022	+	258	WP_081224964.1	phage holin	-
AWC37_RS03350	681450..682397	+	948	WP_081225257.1	peptidoglycan recognition protein family protein	-
AWC37_RS03355	682641..683684	-	1044	WP_081224965.1	hypothetical protein	-
AWC37_RS13825	684214..684375	+	162	WP_155238587.1	hypothetical protein	-
AWC37_RS13830	685519..685686	+	168	WP_155238586.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	640799..690253	49454

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (3-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3760.71 Da
• Isoelectric Point: 10.4997

>T59578 WP_081224963.1 NZ_CP013922:680453-680560 [Staphylococcus xylosus]
VVSIVEALHLMLGFGTFIVTLLGLVIAIVKLSHKK

Nucleotide

• Length: 108 bp

>T59578 NZ_CP013922:680453-680560 [Staphylococcus xylosus]
GTGGTTTCAATTGTAGAAGCGCTACACTTAATGTTAGGTTTCGGTACTTTCATCGTTACCTTATTAGGTTTAGTTATCGC
AATTGTTAAATTAAGCCATAAAAAATAA

Antitoxin

Nucleotide

• Length: 165 bp

>AT59578 NZ_CP013922:c680714-680550 [Staphylococcus xylosus]
ATTTGATAATATTTTTATGTTGTGTTAATTTATATATAGAAAAAGGGCAATACACCATAAGTGTATCGCCCCAGTGAGCC
CGTTAAAAAGACGGTGGCTAGTTACTAATAATTATCAAAAAATAATCATCGAAACCGGCCAAAGTTAGCGATGGTTATTT
TTTAT

Structures

Antitoxin