Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 268028..268536 Replicon chromosome
Accession NZ_CP013916
Organism Sphingomonas sp. LK11

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag AV944_RS01330 Protein ID WP_076714083.1
Coordinates 268270..268536 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag AV944_RS01325 Protein ID WP_056435832.1
Coordinates 268028..268273 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AV944_RS01290 263765..264151 + 387 WP_042485286.1 DUF2141 domain-containing protein -
AV944_RS01295 264263..265108 + 846 WP_076714077.1 MipA/OmpV family protein -
AV944_RS01300 265368..265883 - 516 WP_056435817.1 hypothetical protein -
AV944_RS01305 265948..266391 + 444 WP_076714079.1 DUF1810 domain-containing protein -
AV944_RS01310 266413..266790 - 378 WP_056435823.1 hypothetical protein -
AV944_RS01315 266902..267597 + 696 WP_076714081.1 uracil-DNA glycosylase -
AV944_RS01320 267677..267988 + 312 WP_056435829.1 alkylphosphonate utilization protein -
AV944_RS01325 268028..268273 + 246 WP_056435832.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
AV944_RS01330 268270..268536 + 267 WP_076714083.1 Txe/YoeB family addiction module toxin Toxin
AV944_RS18590 268547..269224 + 678 WP_156884143.1 hypothetical protein -
AV944_RS01335 269236..271083 - 1848 WP_076714085.1 phosphomethylpyrimidine synthase ThiC -
AV944_RS01340 271375..272406 - 1032 WP_076714087.1 ferritin-like domain-containing protein -
AV944_RS01345 272441..273421 - 981 WP_076717732.1 ferritin-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(6-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10387.69 Da        Isoelectric Point: 8.2963

>T59575 WP_076714083.1 NZ_CP013916:268270-268536 [Sphingomonas sp. LK11]
VKVAFWPTAWDDYRHWQEHDAKLCDKLNALIEECRRHPFKGTGKPEPLGGNLSGWWSRRISHEHRLVYRVAGSGEDQVLQ
VAQCRYHY

Download         Length: 267 bp

>T59575 NZ_CP013916:268270-268536 [Sphingomonas sp. LK11]
GTGAAAGTGGCGTTCTGGCCGACGGCGTGGGACGATTATCGCCATTGGCAGGAACATGACGCCAAGCTTTGCGACAAGCT
CAATGCGTTGATCGAGGAATGCCGCCGTCACCCGTTCAAGGGGACGGGCAAGCCCGAACCGTTGGGCGGCAACCTGTCAG
GCTGGTGGTCGCGCCGGATCAGCCATGAGCATCGACTGGTGTACCGGGTGGCAGGCAGCGGCGAGGATCAGGTGCTACAA
GTGGCGCAGTGCCGGTATCATTATTAA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8862.05 Da        Isoelectric Point: 4.5843

>AT59575 WP_056435832.1 NZ_CP013916:268028-268273 [Sphingomonas sp. LK11]
MQAVSYSEARENLKAMIDKVVADRAPVAITRQRGEGAVLISASEWASIEETLYLLRSPKNAERLLDAVRGFEAGDEGVPF
P

Download         Length: 246 bp

>AT59575 NZ_CP013916:268028-268273 [Sphingomonas sp. LK11]
ATGCAGGCTGTCTCCTATTCCGAAGCGCGCGAGAATCTGAAGGCGATGATCGACAAGGTCGTCGCCGACCGCGCGCCCGT
GGCGATCACCCGCCAGCGGGGCGAAGGCGCCGTGCTGATCTCCGCCAGCGAATGGGCGTCGATCGAAGAGACGCTGTACC
TGCTGCGCTCGCCCAAGAATGCCGAACGTCTGCTCGACGCCGTGCGCGGCTTTGAGGCGGGCGACGAAGGCGTGCCCTTT
CCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References