Detailed information of TA system TA059566

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): SprA2-sprA1AS/-
• Location: 72182..72330
• Replicon: chromosome
• Accession: NZ_CP013911
• Organism: Staphylococcus haemolyticus strain S167

Toxin (Protein)

• Gene name: SprA2
• Uniprot ID: -
• Locus tag: AV904_RS12555
• Protein ID: WP_011276848.1
• Coordinates: 72182..72277 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	72295..72330 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
AV904_RS00315	68249..68566	-	318	Protein_62	IS200/IS605-like element ISSep3 family transposase	-
AV904_RS00325	69367..69516	+	150	WP_062931900.1	hypothetical protein	-
AV904_RS00330	70122..70652	+	531	WP_053038729.1	N-acetyltransferase	-
AV904_RS00335	70891..71274	+	384	WP_011276846.1	effector binding domain-containing protein	-
AV904_RS00340	71413..71717	+	305	Protein_66	hypothetical protein	-
AV904_RS12710	71739..71987	+	249	WP_002440480.1	hypothetical protein	-
AV904_RS12555	72182..72277	+	96	WP_011276848.1	type I toxin-antitoxin system Fst family toxin	Toxin
-	72295..72330	+	36	-	-	Antitoxin
AV904_RS00345	72416..73624	-	1209	WP_053021807.1	hypothetical protein	-
AV904_RS00350	73801..74436	-	636	WP_053021806.1	HXXEE domain-containing protein	-
AV904_RS00355	74438..75085	-	648	WP_053021805.1	TetR/AcrR family transcriptional regulator	-
AV904_RS00360	75105..75755	-	651	WP_053021804.1	HXXEE domain-containing protein	-
AV904_RS00365	76014..76592	+	579	WP_037559009.1	recombinase family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3623.38 Da
• Isoelectric Point: 9.5124

>T59566 WP_011276848.1 NZ_CP013911:72182-72277 [Staphylococcus haemolyticus]
MLEILVHITTTVISGCIIALFTHWLRNRKDK

Nucleotide

• Length: 96 bp

>T59566 NZ_CP013911:72182-72277 [Staphylococcus haemolyticus]
ATGTTGGAAATCCTTGTTCACATCACGACCACAGTCATCAGTGGTTGTATTATTGCGTTATTTACGCATTGGCTGCGTAA
TCGCAAAGACAAATAG

Antitoxin

Nucleotide

• Length: 36 bp

>AT59566 NZ_CP013911:72295-72330 [Staphylococcus haemolyticus]
TACAAAAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin