Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2277237..2277500 Replicon chromosome
Accession NZ_CP013621
Organism Staphylococcus aureus strain RIVM3897

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag AUC50_RS11460 Protein ID WP_001802298.1
Coordinates 2277396..2277500 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF2
Locus tag -
Coordinates 2277237..2277401 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AUC50_RS11440 2273422..2274087 - 666 WP_001024099.1 SDR family oxidoreductase -
AUC50_RS11445 2274239..2274559 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
AUC50_RS11450 2274561..2275541 + 981 WP_000019735.1 CDF family zinc efflux transporter CzrB -
AUC50_RS11455 2275807..2276898 + 1092 WP_000495673.1 hypothetical protein -
- 2277237..2277401 + 165 - - Antitoxin
AUC50_RS11460 2277396..2277500 - 105 WP_001802298.1 hypothetical protein Toxin
AUC50_RS15570 2278017..2278187 + 171 WP_001807897.1 hypothetical protein -
AUC50_RS15180 2278180..2278338 + 159 WP_001792784.1 hypothetical protein -
AUC50_RS11465 2278774..2278866 + 93 WP_000220902.1 hypothetical protein -
AUC50_RS11470 2278996..2279853 - 858 WP_000370942.1 Cof-type HAD-IIB family hydrolase -
AUC50_RS11475 2279921..2280703 - 783 WP_060585346.1 ABC transporter ATP-binding protein -
AUC50_RS11480 2280993..2281601 - 609 WP_000101714.1 TIR domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T59048 WP_001802298.1 NZ_CP013621:c2277500-2277396 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T59048 NZ_CP013621:c2277500-2277396 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 165 bp

>AT59048 NZ_CP013621:2277237-2277401 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References