Detailed information of TA system TA059041

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 1075660..1075909
• Replicon: chromosome
• Accession: NZ_CP013621
• Organism: Staphylococcus aureus strain RIVM3897

Toxin (Protein)

• Gene name: SprG2
• Uniprot ID: -
• Locus tag: AUC50_RS05190
• Protein ID: WP_000623369.1
• Coordinates: 1075660..1075767 (+)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprF2
Locus tag	-
Coordinates	1075762..1075909 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
AUC50_RS05165	1072334..1072903	-	570	WP_000287265.1	competence protein ComK	-
AUC50_RS05170	1073113..1073331	+	219	WP_000876826.1	IDEAL domain-containing protein	-
AUC50_RS05175	1073412..1074398	-	987	WP_000668814.1	lipoate--protein ligase	-
AUC50_RS05180	1074597..1074773	+	177	WP_000214898.1	YkvS family protein	-
AUC50_RS05185	1074788..1075390	+	603	WP_001033867.1	CPBP family intramembrane metalloprotease	-
AUC50_RS05190	1075660..1075767	+	108	WP_000623369.1	putative holin-like toxin	Toxin
-	1075762..1075909	-	148	-	-	Antitoxin
AUC50_RS05195	1076402..1076686	+	285	WP_000790905.1	lactococcin 972 family bacteriocin	-
AUC50_RS05200	1076730..1078694	+	1965	WP_000870811.1	bacteriocin-associated integral membrane family protein	-
AUC50_RS05205	1078697..1079017	+	321	WP_000668623.1	YxeA family protein	-
AUC50_RS05210	1079014..1079655	+	642	WP_000571192.1	ABC transporter ATP-binding protein	-
AUC50_RS14915	1079743..1080033	-	291	WP_001796515.1	hypothetical protein	-
AUC50_RS14920	1080123..1080311	+	189	WP_157958947.1	poly(glycerol-phosphate) alpha-glucosyltransferase	-
AUC50_RS05220	1080400..1080756	-	357	WP_000766009.1	DoxX family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (3-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3801.69 Da
• Isoelectric Point: 10.8004

>T59041 WP_000623369.1 NZ_CP013621:1075660-1075767 [Staphylococcus aureus]
VISIANALHLMLSFGMFIVTFIGVVVAIINLNNKK

Nucleotide

• Length: 108 bp

>T59041 NZ_CP013621:1075660-1075767 [Staphylococcus aureus]
GTGATATCTATTGCAAATGCATTACATTTAATGTTAAGTTTCGGTATGTTTATCGTCACTTTCATTGGTGTAGTAGTCGC
AATAATTAATTTAAACAATAAAAAATAA

Antitoxin

Nucleotide

• Length: 148 bp

>AT59041 NZ_CP013621:c1075909-1075762 [Staphylococcus aureus]
CAATTAAATAAAAGATATGTTACTATAAAAATGTAAAAAGACGACATGCAGTAACATGTCGCCTAATGAGCCCGTTAAAA
AGACGGTGACTAAATGAGATTTGCTTTAACCATCATTCGTTGTCAAAGTTTTGAAATGATGGTTATTT

Structures

Antitoxin