Detailed information of TA system TA059038

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): SprA2-sprA1AS/-
• Location: 220780..220928
• Replicon: chromosome
• Accession: NZ_CP013621
• Organism: Staphylococcus aureus strain RIVM3897

Toxin (Protein)

• Gene name: SprA2
• Uniprot ID: -
• Locus tag: AUC50_RS15365
• Protein ID: WP_011276848.1
• Coordinates: 220780..220875 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	220893..220928 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
AUC50_RS14635	217149..217343	+	195	WP_021459082.1	hypothetical protein	-
AUC50_RS00960	217340..218014	-	675	WP_002512555.1	IS6 family transposase	-
AUC50_RS15550	218156..218308	+	153	WP_158501055.1	hypothetical protein	-
AUC50_RS15590	218382..218549	-	168	WP_162837505.1	hypothetical protein	-
AUC50_RS00965	218580..218810	-	231	WP_031884148.1	SHOCT domain-containing protein	-
AUC50_RS15670	218944..219036	-	93	WP_002499091.1	hypothetical protein	-
AUC50_RS00980	219631..220248	+	618	WP_002467537.1	CadD family cadmium resistance transporter	-
AUC50_RS00985	220267..220614	+	348	WP_002467551.1	metalloregulator ArsR/SmtB family transcription factor	-
AUC50_RS15365	220780..220875	+	96	WP_011276848.1	type I toxin-antitoxin system Fst family toxin	Toxin
-	220893..220928	+	36	-	-	Antitoxin
AUC50_RS00990	221230..221703	+	474	WP_077460978.1	thymidylate synthase	-
AUC50_RS00995	221817..222245	+	429	WP_031885498.1	Rrf2 family transcriptional regulator	-
AUC50_RS14640	222366..222941	+	576	Protein_197	DsbA family protein	-
AUC50_RS01005	222958..223608	+	651	WP_031885497.1	NAD(P)-dependent oxidoreductase	-
AUC50_RS01010	223907..224662	-	756	WP_031863945.1	sulfite exporter TauE/SafE family protein	-
AUC50_RS01015	224662..224922	-	261	WP_031863946.1	persulfide-sensing transcriptional repressor CstR	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	flank	IS/Tn	-	-	217340..218014	674

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3623.38 Da
• Isoelectric Point: 9.5124

>T59038 WP_011276848.1 NZ_CP013621:220780-220875 [Staphylococcus aureus]
MLEILVHITTTVISGCIIALFTHWLRNRKDK

Nucleotide

• Length: 96 bp

>T59038 NZ_CP013621:220780-220875 [Staphylococcus aureus]
ATGTTGGAAATCCTTGTTCACATCACGACCACAGTCATCAGTGGTTGTATTATTGCGTTATTTACGCATTGGCTGCGTAA
TCGCAAAGACAAATAG

Antitoxin

Nucleotide

• Length: 36 bp

>AT59038 NZ_CP013621:220893-220928 [Staphylococcus aureus]
TACAAAAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin