59034

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2164373..2164636 Replicon chromosome
Accession NZ_CP013619
Organism Staphylococcus aureus strain RIVM1607

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag AUC49_RS10695 Protein ID WP_001802298.1
Coordinates 2164532..2164636 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF2
Locus tag -
Coordinates 2164373..2164537 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AUC49_RS10675 2160558..2161223 - 666 WP_001024099.1 SDR family oxidoreductase -
AUC49_RS10680 2161375..2161695 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
AUC49_RS10685 2161697..2162677 + 981 WP_000019735.1 CDF family zinc efflux transporter CzrB -
AUC49_RS10690 2162943..2164034 + 1092 WP_000495673.1 hypothetical protein -
- 2164373..2164537 + 165 - - Antitoxin
AUC49_RS10695 2164532..2164636 - 105 WP_001802298.1 hypothetical protein Toxin
AUC49_RS14295 2165316..2165474 + 159 WP_001792784.1 hypothetical protein -
AUC49_RS14300 2165910..2166002 + 93 WP_000220902.1 hypothetical protein -
AUC49_RS10700 2166132..2166989 - 858 WP_000370942.1 Cof-type HAD-IIB family hydrolase -
AUC49_RS10705 2167057..2167839 - 783 WP_000908191.1 ABC transporter ATP-binding protein -
AUC49_RS10710 2168129..2168737 - 609 WP_000101714.1 TIR domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T59034 WP_001802298.1 NZ_CP013619:c2164636-2164532 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T59034 NZ_CP013619:c2164636-2164532 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 165 bp

>AT59034 NZ_CP013619:2164373-2164537 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References