Detailed information of TA system TA059030

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 1044204..1044453
• Replicon: chromosome
• Accession: NZ_CP013619
• Organism: Staphylococcus aureus strain RIVM1607

Toxin (Protein)

• Gene name: SprG2
• Uniprot ID: -
• Locus tag: AUC49_RS05045
• Protein ID: WP_000623369.1
• Coordinates: 1044204..1044311 (+)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprF2
Locus tag	-
Coordinates	1044306..1044453 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
AUC49_RS05020	1040878..1041447	-	570	WP_000287260.1	competence protein ComK	-
AUC49_RS05025	1041657..1041875	+	219	WP_000876826.1	IDEAL domain-containing protein	-
AUC49_RS05030	1041956..1042942	-	987	WP_000668814.1	lipoate--protein ligase	-
AUC49_RS05035	1043141..1043317	+	177	WP_000214898.1	YkvS family protein	-
AUC49_RS05040	1043332..1043934	+	603	WP_001033867.1	CPBP family intramembrane metalloprotease	-
AUC49_RS05045	1044204..1044311	+	108	WP_000623369.1	putative holin-like toxin	Toxin
-	1044306..1044453	-	148	-	-	Antitoxin
AUC49_RS05050	1044946..1045230	+	285	WP_000790905.1	lactococcin 972 family bacteriocin	-
AUC49_RS05055	1045274..1047238	+	1965	WP_000870811.1	bacteriocin-associated integral membrane family protein	-
AUC49_RS05060	1047241..1047561	+	321	WP_000668623.1	YxeA family protein	-
AUC49_RS05065	1047558..1048199	+	642	WP_000571192.1	ABC transporter ATP-binding protein	-
AUC49_RS14075	1048287..1048577	-	291	WP_001796515.1	hypothetical protein	-
AUC49_RS14080	1048667..1048855	+	189	WP_157958947.1	poly(glycerol-phosphate) alpha-glucosyltransferase	-
AUC49_RS05075	1048944..1049300	-	357	WP_000766009.1	DoxX family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (3-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3801.69 Da
• Isoelectric Point: 10.8004

>T59030 WP_000623369.1 NZ_CP013619:1044204-1044311 [Staphylococcus aureus]
VISIANALHLMLSFGMFIVTFIGVVVAIINLNNKK

Nucleotide

• Length: 108 bp

>T59030 NZ_CP013619:1044204-1044311 [Staphylococcus aureus]
GTGATATCTATTGCAAATGCATTACATTTAATGTTAAGTTTCGGTATGTTTATCGTCACTTTCATTGGTGTAGTAGTCGC
AATAATTAATTTAAACAATAAAAAATAA

Antitoxin

Nucleotide

• Length: 148 bp

>AT59030 NZ_CP013619:c1044453-1044306 [Staphylococcus aureus]
CAATTAAATAAAAGATATGTTACTATAAAAATGTAAAAAGACGACATGCAGTAACATGTCGCCTAATGAGCCCGTTAAAA
AGACGGTGACTAAATGAGATTTGCTTTAACCATCATTCGTTGTCAAAGTTTTGAAATGATGGTTATTT

Structures

Antitoxin