Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 1326562..1327261 Replicon chromosome
Accession NZ_CP013466
Organism Burkholderia multivorans strain MSMB1640WGS

Toxin (Protein)


Gene name mqsR Uniprot ID -
Locus tag WM33_RS05795 Protein ID WP_048804722.1
Coordinates 1326562..1326858 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID -
Locus tag WM33_RS05800 Protein ID WP_048804721.1
Coordinates 1326860..1327261 (+) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
WM33_RS05780 1323283..1324827 + 1545 WP_167541822.1 sensor domain-containing diguanylate cyclase -
WM33_RS05785 1325033..1325305 + 273 WP_012216969.1 hypothetical protein -
WM33_RS05790 1325408..1326442 + 1035 WP_006397017.1 succinylglutamate desuccinylase/aspartoacylase family protein -
WM33_RS05795 1326562..1326858 + 297 WP_048804722.1 type II toxin-antitoxin system MqsR family toxin Toxin
WM33_RS05800 1326860..1327261 + 402 WP_048804721.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
WM33_RS05805 1327550..1328110 + 561 WP_048804720.1 GNAT family N-acetyltransferase -
WM33_RS05810 1328176..1329117 + 942 WP_006397013.1 ABC transporter substrate-binding protein -
WM33_RS05815 1329149..1330210 + 1062 WP_048804719.1 LLM class flavin-dependent oxidoreductase -
WM33_RS05820 1330207..1331559 + 1353 WP_006413139.1 LLM class flavin-dependent oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(2-97)

Antitoxin

Antitoxin MqsA/HigA-2

(1-131)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11185.07 Da        Isoelectric Point: 9.1122

>T58723 WP_048804722.1 NZ_CP013466:1326562-1326858 [Burkholderia multivorans]
MEKRTPHCKLPRVKALVEAGKVRLTASAVIGARQMGFTEAETIDVVRALTPFEFHKSMTTYADHTIWQDVYRPCTMRGDV
YLKLTVVDDVLIVSFKER

Download         Length: 297 bp

>T58723 NZ_CP013466:1326562-1326858 [Burkholderia multivorans]
ATGGAAAAGAGAACGCCGCATTGCAAGCTGCCGCGCGTCAAGGCGCTGGTCGAAGCCGGCAAGGTCCGCCTGACCGCAAG
CGCCGTCATCGGCGCCCGCCAGATGGGCTTCACCGAAGCGGAAACGATCGACGTGGTAAGGGCGCTGACACCGTTCGAAT
TCCACAAGAGCATGACGACCTACGCCGACCACACGATCTGGCAGGACGTCTACCGGCCTTGCACGATGCGCGGCGACGTG
TATCTGAAACTGACCGTCGTCGACGATGTGCTGATCGTGTCTTTCAAGGAGCGATGA

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14521.68 Da        Isoelectric Point: 7.0834

>AT58723 WP_048804721.1 NZ_CP013466:1326860-1327261 [Burkholderia multivorans]
MKCPACGAATLIRDTRDIPYTYKGESTVIPHVTGEFCPACGESVLDVDEATRFGEAVSAFNRQVNATLVDPKFIATVRKK
LKLDQREAAEIFGGGVNAFSRYETGKTNPPLALVKLLKLLDRHPDLLDEVRAA

Download         Length: 402 bp

>AT58723 NZ_CP013466:1326860-1327261 [Burkholderia multivorans]
ATGAAATGTCCTGCATGCGGCGCCGCCACGCTGATCCGCGATACGCGCGACATCCCGTACACCTACAAGGGCGAATCGAC
CGTGATCCCGCACGTCACCGGCGAGTTTTGCCCCGCGTGCGGCGAGTCGGTGCTCGACGTCGACGAGGCGACCCGTTTCG
GCGAAGCGGTGTCGGCGTTCAATCGGCAAGTGAATGCGACACTCGTCGATCCGAAGTTCATTGCGACGGTGCGCAAGAAG
CTGAAGCTCGATCAGCGCGAGGCGGCCGAGATTTTCGGCGGCGGCGTCAACGCGTTTTCCCGCTACGAGACCGGCAAGAC
CAATCCGCCGCTGGCGCTCGTGAAGCTGCTGAAGCTTCTCGACCGTCATCCCGATCTGCTCGACGAAGTGCGCGCGGCAT
AA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References