Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/Tad-HTH_37
Location 160023..160680 Replicon chromosome
Accession NZ_CP013400
Organism Burkholderia seminalis strain FL-5-4-10-S1-D7

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag WJ12_RS21440 Protein ID WP_049029955.1
Coordinates 160023..160355 (+) Length 111 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag WJ12_RS21445 Protein ID WP_049029949.1
Coordinates 160348..160680 (+) Length 111 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
WJ12_RS36025 155742..155933 + 192 WP_156444716.1 hypothetical protein -
WJ12_RS21430 156091..159396 + 3306 WP_059556337.1 autotransporter outer membrane beta-barrel domain-containing protein -
WJ12_RS21435 159536..159685 + 150 WP_154233778.1 hypothetical protein -
WJ12_RS21440 160023..160355 + 333 WP_049029955.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
WJ12_RS21445 160348..160680 + 333 WP_049029949.1 helix-turn-helix domain-containing protein Antitoxin
WJ12_RS21450 160736..161575 - 840 WP_059556336.1 AraC family transcriptional regulator -
WJ12_RS21455 161724..162458 - 735 WP_059556335.1 fucose-binding lectin II -
WJ12_RS21460 162609..163415 - 807 WP_034189646.1 fucose-binding lectin II -
WJ12_RS21465 163539..163928 - 390 WP_034189645.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(18-104)

Antitoxin

Cro/C1-type helix-turn-helix domain

(52-105)


Sequences

Toxin        


Download         Length: 111 a.a.        Molecular weight: 12915.06 Da        Isoelectric Point: 10.0669

>T58588 WP_049029955.1 NZ_CP013400:160023-160355 [Burkholderia seminalis]
MKKWTILYYDERVKRDVFALPKGILAGYLRLIETMEEYGADLRMPHSRAMGEGLFELRPRGREGIGRVFYCMQVGYDLVV
LHSFVKKTQETSGDELRIARRRMKEVRNNG

Download         Length: 333 bp

>T58588 NZ_CP013400:160023-160355 [Burkholderia seminalis]
ATGAAGAAGTGGACGATCCTGTACTACGACGAACGAGTAAAACGTGATGTGTTCGCTTTGCCCAAGGGCATTCTGGCTGG
CTACCTCCGACTGATCGAGACGATGGAAGAATACGGTGCGGATCTACGGATGCCGCATTCGCGCGCGATGGGGGAAGGAT
TGTTTGAGTTGCGCCCGCGAGGTCGCGAGGGCATCGGGCGCGTGTTCTATTGCATGCAGGTGGGGTATGACCTCGTCGTC
CTGCATTCCTTCGTCAAGAAGACCCAGGAAACATCCGGCGACGAGTTGCGAATCGCCCGCCGGCGAATGAAGGAGGTACG
TAACAATGGCTAA

Antitoxin


Download         Length: 111 a.a.        Molecular weight: 11981.51 Da        Isoelectric Point: 8.0754

>AT58588 WP_049029949.1 NZ_CP013400:160348-160680 [Burkholderia seminalis]
MAKARHAHASEERYAPVRHTAEDTARLLTDPAIKAEYDALEEEFTALRALLDARKDAGLTQAQVAERMGTTTSAVSRLEA
SFSSEKHSPSFATLRKYAAACGKKLVISFA

Download         Length: 333 bp

>AT58588 NZ_CP013400:160348-160680 [Burkholderia seminalis]
ATGGCTAAGGCCCGCCACGCGCATGCAAGCGAGGAGCGGTATGCACCGGTCCGACACACTGCCGAAGACACCGCGCGTCT
ACTTACCGATCCGGCGATCAAGGCGGAGTACGATGCGCTGGAAGAGGAGTTCACCGCGCTTCGTGCGTTGCTCGACGCGC
GTAAAGACGCGGGCCTGACTCAGGCTCAGGTCGCCGAACGAATGGGCACTACGACATCGGCCGTATCCAGGCTCGAAGCT
TCGTTTTCGAGCGAGAAGCACTCGCCGTCGTTTGCGACGCTGCGCAAGTACGCCGCAGCGTGCGGCAAGAAGCTCGTCAT
TTCGTTCGCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References