Detailed information of TA system TA058172

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): prlF-yhaV (relBE)/YhaV-PrlF
• Location: 24179..25020
• Replicon: chromosome
• Accession: NZ_CP013236
• Organism: Collimonas pratensis strain Ter291

Toxin (Protein)

• Gene name: yhaV
• Uniprot ID: -
• Locus tag: CPter291_RS00085
• Protein ID: WP_062111215.1
• Coordinates: 24179..24694 (-)
• Length: 172 a.a.

Antitoxin (Protein)

• Gene name: prlF
• Uniprot ID: A0A127QQM6
• Locus tag: CPter291_RS00090
• Protein ID: WP_062111217.1
• Coordinates: 24691..25020 (-)
• Length: 110 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CPter291_RS00065	19481..20311	-	831	WP_062111207.1	HNH endonuclease	-
CPter291_RS00070	20539..21378	+	840	WP_156479854.1	hypothetical protein	-
CPter291_RS25125	21491..21703	-	213	WP_082806867.1	helix-turn-helix domain-containing protein	-
CPter291_RS25130	21915..22157	+	243	WP_197481624.1	SymE family type I addiction module toxin	-
CPter291_RS00075	22423..22980	+	558	WP_062111211.1	hypothetical protein	-
CPter291_RS00080	22977..23918	+	942	WP_062111213.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	-
CPter291_RS00085	24179..24694	-	516	WP_062111215.1	type II toxin-antitoxin system YhaV family toxin	Toxin
CPter291_RS00090	24691..25020	-	330	WP_062111217.1	type II toxin-antitoxin system PrlF family antitoxin	Antitoxin
CPter291_RS00100	25499..26431	-	933	WP_062111221.1	AraC family transcriptional regulator	-
CPter291_RS00105	26532..27275	+	744	WP_062111223.1	SDR family oxidoreductase	-
CPter291_RS00110	27293..27676	-	384	WP_061935312.1	pentapeptide repeat-containing protein	-
CPter291_RS00115	27959..28276	+	318	WP_062111225.1	helix-turn-helix domain-containing protein	-
CPter291_RS00120	28273..29517	+	1245	WP_062111227.1	type II toxin-antitoxin system HipA family toxin	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin endonuclease, YhaV (16-152)

Antitoxin

• PrlF antitoxin (8-107)

Sequences

Toxin

Protein

• Length: 172 a.a.
• Molecular weight: 19776.39 Da
• Isoelectric Point: 8.4120

>T58172 WP_062111215.1 NZ_CP013236:c24694-24179 [Collimonas pratensis]
MTDSKPAHLVVNGWTVFAHPLFLAQLETLMRRVEALKQKDPAGYTEKNASKRLAAIAKLAFEVIPQDPSRAEYRQGNTLG
EDHKHWFRAKFFQQYRLFFRYHAPSKVIVYAWVNDEGTKRAYESSDDAYRVFRTMLESGHPPDDWDQLLVEARSEGDRLQ
RIAAAEPLVQP

Nucleotide

• Length: 516 bp

>T58172 NZ_CP013236:c24694-24179 [Collimonas pratensis]
ATGACCGACAGCAAACCTGCGCACCTGGTCGTCAACGGGTGGACAGTTTTCGCTCACCCGCTGTTCCTTGCGCAACTTGA
AACGCTGATGCGGCGGGTCGAGGCACTCAAGCAAAAAGATCCCGCCGGATACACAGAAAAGAACGCCAGCAAGCGGCTGG
CAGCAATCGCCAAACTGGCGTTCGAGGTGATTCCGCAAGATCCGTCGCGGGCCGAATACCGGCAGGGCAACACCCTCGGC
GAAGACCACAAGCACTGGTTCCGAGCCAAGTTCTTCCAGCAGTACCGGCTGTTCTTCCGCTACCATGCGCCAAGCAAAGT
GATCGTCTACGCATGGGTGAACGACGAGGGCACCAAGCGCGCCTACGAGAGCAGCGACGATGCCTACCGGGTGTTCCGCA
CGATGCTAGAGAGCGGCCATCCCCCGGACGACTGGGATCAACTATTGGTCGAGGCGCGTTCCGAAGGCGACCGTCTGCAG
CGTATCGCGGCAGCGGAGCCACTGGTGCAGCCCTGA

Antitoxin

Protein

• Length: 110 a.a.
• Molecular weight: 12131.61 Da
• Isoelectric Point: 4.3953

>AT58172 WP_062111217.1 NZ_CP013236:c25020-24691 [Collimonas pratensis]
MTATLEVESTLTDRYQTTVPETVRRALRLNKRDKIHYTIRPGGEVVLSRVEAAEEEDPVLGQFLGFLARDIASHPERLQA
VDANFVQRIQSLVGSVEVDLDAALPADDE

Nucleotide

• Length: 330 bp

>AT58172 NZ_CP013236:c25020-24691 [Collimonas pratensis]
ATGACCGCCACCCTTGAAGTCGAATCGACCCTGACCGATCGCTACCAGACAACAGTGCCGGAAACCGTTCGCCGCGCCCT
GAGGCTGAACAAGCGGGACAAGATTCACTACACGATCCGCCCCGGCGGTGAGGTCGTACTCTCCCGCGTGGAAGCGGCCG
AGGAAGAGGACCCGGTGCTCGGGCAGTTCCTGGGCTTTCTGGCCCGCGACATTGCCAGCCATCCGGAACGACTCCAAGCC
GTCGACGCCAATTTCGTGCAACGCATTCAGTCGCTGGTCGGCAGTGTTGAAGTCGATCTGGATGCCGCCTTGCCGGCAGA
TGATGAATGA

Structures

Antitoxin

• AlphaFold DB: A0A127QQM6