Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 1294726..1294943 Replicon chromosome
Accession NZ_CP013231
Organism Staphylococcus aureus strain UTSW MRSA 55

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag AS858_RS07555 Protein ID WP_001802298.1
Coordinates 1294839..1294943 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 1294726..1294781 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AS858_RS07535 1290863..1291528 - 666 WP_001024094.1 SDR family oxidoreductase -
AS858_RS07540 1291680..1292000 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
AS858_RS07545 1292002..1292982 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
AS858_RS07550 1293248..1294339 + 1092 WP_000495671.1 lytic regulatory protein -
- 1294726..1294781 + 56 - - Antitoxin
AS858_RS07555 1294839..1294943 - 105 WP_001802298.1 hypothetical protein Toxin
AS858_RS17000 1295104..1295587 - 484 Protein_1278 recombinase family protein -
AS858_RS07565 1295630..1296766 - 1137 WP_000115564.1 SAP domain-containing protein -
AS858_RS07570 1297055..1297147 + 93 WP_001790138.1 hypothetical protein -
AS858_RS07575 1297852..1298709 - 858 WP_000370924.1 Cof-type HAD-IIB family hydrolase -
AS858_RS07580 1298777..1299559 - 783 WP_000908176.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T58145 WP_001802298.1 NZ_CP013231:c1294943-1294839 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T58145 NZ_CP013231:c1294943-1294839 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTTATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 56 bp

>AT58145 NZ_CP013231:1294726-1294781 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References