Detailed information of TA system TA058135

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 959071..959253
• Replicon: chromosome
• Accession: NZ_CP013231
• Organism: Staphylococcus aureus strain UTSW MRSA 55

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: AS858_RS16770
• Protein ID: WP_001801861.1
• Coordinates: 959071..959166 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	959194..959253 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
AS858_RS05530	954731..955357	+	627	Protein_918	hypothetical protein	-
AS858_RS05535	955398..955742	+	345	WP_000627551.1	DUF3969 family protein	-
AS858_RS05540	955840..956391	+	552	WP_000414205.1	hypothetical protein	-
AS858_RS05545	956609..957250	-	642	WP_000494956.1	ImmA/IrrE family metallo-endopeptidase	-
AS858_RS05550	957364..957549	-	186	WP_000809857.1	hypothetical protein	-
AS858_RS05555	957551..957727	-	177	WP_000375476.1	hypothetical protein	-
AS858_RS05560	957738..958121	-	384	WP_000070811.1	hypothetical protein	-
AS858_RS05570	958725..958868	-	144	WP_001549059.1	transposase	-
AS858_RS16770	959071..959166	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	959194..959253	-	60	-	-	Antitoxin
AS858_RS05575	959289..959390	+	102	WP_001791893.1	hypothetical protein	-
AS858_RS15975	959368..959544	-	177	Protein_928	transposase	-
AS858_RS05580	959738..960115	-	378	WP_001037045.1	DUF1433 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	952171..977773	25602

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T58135 WP_001801861.1 NZ_CP013231:959071-959166 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T58135 NZ_CP013231:959071-959166 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 60 bp

>AT58135 NZ_CP013231:c959253-959194 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin