58036

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2437585..2437769 Replicon chromosome
Accession NZ_CP013182
Organism Staphylococcus aureus strain SA40TW

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag SA40TW_RS12725 Protein ID WP_000482647.1
Coordinates 2437662..2437769 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2437585..2437645 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SA40TW_RS12700 2433095..2433262 - 168 WP_031845053.1 hypothetical protein -
SA40TW_RS12710 2433493..2435226 - 1734 WP_000488493.1 ABC transporter ATP-binding protein/permease -
SA40TW_RS12715 2435302..2437014 - 1713 WP_001064821.1 ABC transporter ATP-binding protein/permease -
- 2437585..2437645 + 61 - - Antitoxin
SA40TW_RS12725 2437662..2437769 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
SA40TW_RS12730 2437902..2438288 - 387 WP_000779353.1 flippase GtxA -
SA40TW_RS12735 2438556..2439698 + 1143 WP_001176863.1 glycerate kinase -
SA40TW_RS12740 2439758..2440417 + 660 WP_000831298.1 membrane protein -
SA40TW_RS12745 2440600..2441811 + 1212 WP_001191921.1 multidrug effflux MFS transporter -
SA40TW_RS12750 2441934..2442407 - 474 WP_000456483.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T58036 WP_000482647.1 NZ_CP013182:c2437769-2437662 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T58036 NZ_CP013182:c2437769-2437662 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT58036 NZ_CP013182:2437585-2437645 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References