Detailed information of TA system TA058034

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 2150865..2151082
• Replicon: chromosome
• Accession: NZ_CP013182
• Organism: Staphylococcus aureus strain SA40TW

Toxin (Protein)

• Gene name: SprG3
• Uniprot ID: Q2FWA7
• Locus tag: SA40TW_RS11180
• Protein ID: WP_001802298.1
• Coordinates: 2150978..2151082 (-)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	SprF2
Locus tag	-
Coordinates	2150865..2150920 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SA40TW_RS11160	2147056..2147721	-	666	WP_001024088.1	SDR family oxidoreductase	-
SA40TW_RS11165	2147873..2148193	+	321	WP_000139802.1	Zn(II)-responsive metalloregulatory transcriptional repressor CzrA	-
SA40TW_RS11170	2148195..2149172	+	978	WP_000019732.1	CDF family zinc efflux transporter CzrB	-
SA40TW_RS11175	2149438..2150529	+	1092	WP_000495695.1	hypothetical protein	-
-	2150865..2150920	+	56	-	-	Antitoxin
SA40TW_RS11180	2150978..2151082	-	105	WP_001802298.1	hypothetical protein	Toxin
SA40TW_RS14740	2151243..2151726	-	484	Protein_2025	recombinase family protein	-
SA40TW_RS11190	2151769..2152905	-	1137	Protein_2026	SAP domain-containing protein	-
SA40TW_RS11195	2153194..2153286	+	93	WP_031844941.1	hypothetical protein	-
SA40TW_RS11200	2153981..2154838	-	858	WP_000370919.1	Cof-type HAD-IIB family hydrolase	-
SA40TW_RS11205	2154906..2155688	-	783	WP_000908190.1	ABC transporter ATP-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3906.77 Da
• Isoelectric Point: 5.5724

>T58034 WP_001802298.1 NZ_CP013182:c2151082-2150978 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Nucleotide

• Length: 105 bp

>T58034 NZ_CP013182:c2151082-2150978 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin

Nucleotide

• Length: 56 bp

>AT58034 NZ_CP013182:2150865-2150920 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Structures

Toxin

• AlphaFold DB: A0A2I7Y9L9

Antitoxin