58033

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2150819..2151082 Replicon chromosome
Accession NZ_CP013182
Organism Staphylococcus aureus strain SA40TW

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag SA40TW_RS11180 Protein ID WP_001802298.1
Coordinates 2150978..2151082 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF2
Locus tag -
Coordinates 2150819..2150983 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SA40TW_RS11160 2147056..2147721 - 666 WP_001024088.1 SDR family oxidoreductase -
SA40TW_RS11165 2147873..2148193 + 321 WP_000139802.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
SA40TW_RS11170 2148195..2149172 + 978 WP_000019732.1 CDF family zinc efflux transporter CzrB -
SA40TW_RS11175 2149438..2150529 + 1092 WP_000495695.1 hypothetical protein -
- 2150819..2150983 + 165 - - Antitoxin
SA40TW_RS11180 2150978..2151082 - 105 WP_001802298.1 hypothetical protein Toxin
SA40TW_RS14740 2151243..2151726 - 484 Protein_2025 recombinase family protein -
SA40TW_RS11190 2151769..2152905 - 1137 Protein_2026 SAP domain-containing protein -
SA40TW_RS11195 2153194..2153286 + 93 WP_031844941.1 hypothetical protein -
SA40TW_RS11200 2153981..2154838 - 858 WP_000370919.1 Cof-type HAD-IIB family hydrolase -
SA40TW_RS11205 2154906..2155688 - 783 WP_000908190.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T58033 WP_001802298.1 NZ_CP013182:c2151082-2150978 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T58033 NZ_CP013182:c2151082-2150978 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 165 bp

>AT58033 NZ_CP013182:2150819-2150983 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References