Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 1989005..1989189 Replicon chromosome
Accession NZ_CP013137
Organism Staphylococcus aureus strain XQ

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag ASU36_RS10400 Protein ID WP_000482647.1
Coordinates 1989082..1989189 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 1989005..1989065 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ASU36_RS10375 1984459..1984626 - 168 WP_031927726.1 hypothetical protein -
ASU36_RS10385 1984857..1986590 - 1734 WP_000486497.1 ABC transporter ATP-binding protein/permease -
ASU36_RS10390 1986615..1988378 - 1764 WP_031927727.1 ABC transporter ATP-binding protein/permease -
- 1989005..1989065 + 61 - - Antitoxin
ASU36_RS10400 1989082..1989189 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
ASU36_RS10405 1989323..1989709 - 387 WP_000779353.1 flippase GtxA -
ASU36_RS10410 1989977..1991119 + 1143 WP_031927728.1 glycerate kinase -
ASU36_RS10415 1991179..1991838 + 660 WP_031927729.1 membrane protein -
ASU36_RS10420 1992020..1993231 + 1212 WP_001191927.1 multidrug effflux MFS transporter -
ASU36_RS10425 1993354..1993827 - 474 WP_000456493.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T58006 WP_000482647.1 NZ_CP013137:c1989189-1989082 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T58006 NZ_CP013137:c1989189-1989082 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT58006 NZ_CP013137:1989005-1989065 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References