Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 1702986..1703249 Replicon chromosome
Accession NZ_CP013137
Organism Staphylococcus aureus strain XQ

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag ASU36_RS08790 Protein ID WP_001802298.1
Coordinates 1703145..1703249 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF2
Locus tag -
Coordinates 1702986..1703150 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ASU36_RS08770 1699163..1699828 - 666 WP_001024091.1 SDR family oxidoreductase -
ASU36_RS08775 1699980..1700300 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
ASU36_RS08780 1700302..1701282 + 981 WP_000019739.1 CDF family zinc efflux transporter CzrB -
ASU36_RS08785 1701548..1702639 + 1092 WP_000495694.1 hypothetical protein -
- 1702986..1703150 + 165 - - Antitoxin
ASU36_RS08790 1703145..1703249 - 105 WP_001802298.1 hypothetical protein Toxin
ASU36_RS15120 1703410..1703907 - 498 Protein_1669 recombinase family protein -
ASU36_RS08800 1703957..1705084 - 1128 WP_000115558.1 SAP domain-containing protein -
ASU36_RS08810 1706133..1706990 - 858 WP_000370936.1 Cof-type HAD-IIB family hydrolase -
ASU36_RS08815 1707058..1707840 - 783 WP_000908193.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(6-112)


Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T58003 WP_001802298.1 NZ_CP013137:c1703249-1703145 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T58003 NZ_CP013137:c1703249-1703145 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 165 bp

>AT58003 NZ_CP013137:1702986-1703150 [Staphylococcus aureus]
GTAGTAAGTAGAAGTAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References