Detailed information of TA system TA057998

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-MW1433/-
• Location: 1527916..1528222
• Replicon: chromosome
• Accession: NZ_CP013137
• Organism: Staphylococcus aureus strain XQ

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: ASU36_RS14675
• Protein ID: WP_078157113.1
• Coordinates: 1528037..1528222 (-)
• Length: 62 a.a.

Antitoxin (RNA)

Gene name	MW1433
Locus tag	-
Coordinates	1527916..1528054 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ASU36_RS07725	1523485..1523664	+	180	WP_000669791.1	hypothetical protein	-
ASU36_RS07735	1523975..1524235	+	261	WP_001791826.1	hypothetical protein	-
ASU36_RS07740	1524287..1524637	-	351	WP_000702263.1	complement inhibitor SCIN-A	-
ASU36_RS07745	1525147..1525482	-	336	Protein_1471	SH3 domain-containing protein	-
ASU36_RS07750	1526132..1526623	-	492	WP_000920038.1	staphylokinase	-
ASU36_RS07755	1526814..1527569	-	756	WP_000861038.1	CHAP domain-containing protein	-
ASU36_RS07760	1527581..1527835	-	255	WP_000611512.1	phage holin	-
ASU36_RS07765	1527887..1527994	+	108	WP_031762631.1	hypothetical protein	-
-	1527916..1528054	+	139	NuclAT_0	-	Antitoxin
-	1527916..1528054	+	139	NuclAT_0	-	Antitoxin
-	1527916..1528054	+	139	NuclAT_0	-	Antitoxin
-	1527916..1528054	+	139	NuclAT_0	-	Antitoxin
ASU36_RS14675	1528037..1528222	-	186	WP_078157113.1	putative holin-like toxin	Toxin
ASU36_RS07770	1528365..1528739	-	375	WP_000340977.1	hypothetical protein	-
ASU36_RS07775	1528795..1529082	-	288	WP_001040255.1	hypothetical protein	-
ASU36_RS07780	1529129..1529281	-	153	WP_000654329.1	hypothetical protein	-
ASU36_RS07785	1529271..1533056	-	3786	WP_031927805.1	phage minor structural protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	scn / sak / hlb / groEL	1524287..1579611	55324

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (30-57)

Sequences

Toxin

Protein

• Length: 62 a.a.
• Molecular weight: 7256.84 Da
• Isoelectric Point: 10.8243

>T57998 WP_078157113.1 NZ_CP013137:c1528222-1528037 [Staphylococcus aureus]
MDRWWLSEYKEVVPMLALLKSLERRRLMITISTMLQFGLFLIALIGLVIKLIELSNKNNHR

Nucleotide

• Length: 186 bp

>T57998 NZ_CP013137:c1528222-1528037 [Staphylococcus aureus]
TTGGATAGATGGTGGCTATCTGAGTATAAGGAGGTGGTGCCTATGTTGGCATTACTGAAATCTTTAGAAAGGAGACGCCT
AATGATTACAATTAGTACCATGTTGCAGTTTGGTTTATTCCTTATTGCATTGATAGGTCTAGTAATCAAGCTTATTGAAT
TAAGCAATAAAAATAACCATCGCTAA

Antitoxin

Nucleotide

• Length: 139 bp

>AT57998 NZ_CP013137:1527916-1528054 [Staphylococcus aureus]
ATATATAGAAAAAGGGCAACATGCGCAAACATGTTACCCTAGTGAGCCCGTTAAAAAGACGGTGGCTATTTTAGATTAAA
GATTAAATTAATAACCATTTAACCATCGAAACCAGCCAAAGTTAGCGATGGTTATTTTT

Structures

Antitoxin