Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 3653244..3653905 Replicon chromosome
Accession NZ_CP013136
Organism Herbaspirillum seropedicae strain AU14040

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag hsc_RS15965 Protein ID WP_069374460.1
Coordinates 3653564..3653905 (-) Length 114 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag hsc_RS15960 Protein ID WP_069374459.1
Coordinates 3653244..3653564 (-) Length 107 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
hsc_RS15940 3649489..3649719 - 231 WP_041311032.1 hypothetical protein -
hsc_RS15945 3649862..3651253 - 1392 WP_069374457.1 ABC transporter substrate-binding protein -
hsc_RS15950 3651362..3652123 - 762 WP_069374458.1 glucose 1-dehydrogenase -
hsc_RS15955 3652312..3653031 - 720 WP_013235261.1 FadR family transcriptional regulator -
hsc_RS15960 3653244..3653564 - 321 WP_069374459.1 transcriptional regulator Antitoxin
hsc_RS15965 3653564..3653905 - 342 WP_069374460.1 toxin Toxin
hsc_RS15970 3654046..3654951 + 906 WP_069374461.1 LysR family transcriptional regulator -
hsc_RS15975 3655090..3655944 + 855 WP_069374462.1 putative hydro-lyase -
hsc_RS15980 3656049..3657293 + 1245 WP_069374463.1 MFS transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(43-89)


Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 13614.76 Da        Isoelectric Point: 10.2194

>T57990 WP_069374460.1 NZ_CP013136:c3653905-3653564 [Herbaspirillum seropedicae]
MDAIFRETRMFEAVRENYLPDGAFAELQQLLMKHPHAGRLIKDLGGLRKIRFPDARRCKGKRGGLRVIYYFWDEKRHFWL
FSIYDKDEMNDLTAEQRKLLRRALENEIARREA

Download         Length: 342 bp

>T57990 NZ_CP013136:c3653905-3653564 [Herbaspirillum seropedicae]
ATGGATGCCATCTTCAGAGAAACGCGAATGTTCGAAGCAGTCCGGGAGAATTACCTTCCGGATGGCGCCTTTGCAGAGCT
TCAACAACTGCTGATGAAGCATCCACACGCGGGCAGACTGATCAAGGATCTGGGTGGGCTGAGGAAGATTCGTTTTCCTG
ATGCACGCCGTTGCAAGGGAAAACGCGGTGGCTTGCGTGTCATCTATTATTTCTGGGACGAGAAACGGCACTTCTGGCTT
TTCTCGATTTACGACAAGGATGAAATGAACGACCTGACTGCCGAGCAGCGCAAGCTGCTCAGGCGCGCTCTGGAGAATGA
AATAGCCCGAAGGGAGGCGTGA

Antitoxin


Download         Length: 107 a.a.        Molecular weight: 11871.77 Da        Isoelectric Point: 11.0226

>AT57990 WP_069374459.1 NZ_CP013136:c3653564-3653244 [Herbaspirillum seropedicae]
MKKRNLFDELMAGVQDMAAEREGKLTLRTTKAALPPEPVSITAEEIQRVRNKARVSQAIMARSLRVNPRTYQNWEQGVSR
PNAQAAVLLKLVDQDPSLFARISALV

Download         Length: 321 bp

>AT57990 NZ_CP013136:c3653564-3653244 [Herbaspirillum seropedicae]
ATGAAGAAGAGAAACTTGTTCGACGAGCTGATGGCTGGCGTCCAAGACATGGCCGCTGAGCGCGAGGGAAAGCTGACCCT
GCGCACTACCAAGGCCGCTTTGCCGCCCGAGCCAGTCTCAATCACTGCGGAGGAGATTCAACGGGTACGCAATAAAGCAC
GCGTTTCGCAAGCCATCATGGCTCGCAGTCTGCGCGTTAATCCCCGCACATATCAGAACTGGGAACAGGGTGTCTCTCGA
CCTAACGCCCAGGCAGCTGTCTTGCTGAAGCTGGTTGATCAGGATCCCAGTCTTTTTGCTCGGATCAGCGCACTGGTATG
A

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References