Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 2842514..2843221 Replicon chromosome
Accession NZ_CP013136
Organism Herbaspirillum seropedicae strain AU14040

Toxin (Protein)


Gene name mqsR Uniprot ID -
Locus tag hsc_RS12395 Protein ID WP_069374078.1
Coordinates 2842919..2843221 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID -
Locus tag hsc_RS12390 Protein ID WP_013234491.1
Coordinates 2842514..2842915 (-) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
hsc_RS12365 2837611..2838804 + 1194 WP_069374074.1 NO-inducible flavohemoprotein -
hsc_RS12370 2838854..2839261 + 408 WP_041311897.1 hemerythrin domain-containing protein -
hsc_RS12375 2839438..2839794 + 357 WP_069374075.1 hypothetical protein -
hsc_RS12380 2839795..2840787 - 993 WP_069374076.1 2-hydroxyacid dehydrogenase -
hsc_RS12385 2841126..2842412 + 1287 WP_069374077.1 MFS transporter -
hsc_RS12390 2842514..2842915 - 402 WP_013234491.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
hsc_RS12395 2842919..2843221 - 303 WP_069374078.1 type II toxin-antitoxin system MqsR family toxin Toxin
hsc_RS12400 2843560..2845788 + 2229 WP_069374079.1 NADP-dependent isocitrate dehydrogenase -
hsc_RS12405 2846103..2846972 - 870 WP_069374080.1 ethanolamine ammonia-lyase subunit EutC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(5-99)

Antitoxin

Antitoxin MqsA

(3-131)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11092.99 Da        Isoelectric Point: 9.2564

>T57989 WP_069374078.1 NZ_CP013136:c2843221-2842919 [Herbaspirillum seropedicae]
MDKHTAHCKLPVVRKLIEAGKVKATATAFQGARACGIGDLDGICAVILGLRPRDFHKSMTTHADHRVWQDVYHTRLHNGM
VAYLKLSVVDDVLVVSFKEL

Download         Length: 303 bp

>T57989 NZ_CP013136:c2843221-2842919 [Herbaspirillum seropedicae]
ATGGATAAGCATACCGCCCACTGCAAGCTGCCCGTGGTCAGGAAACTGATCGAAGCAGGGAAGGTGAAGGCGACCGCTAC
CGCCTTCCAGGGCGCGAGGGCGTGCGGCATCGGGGACCTTGATGGCATCTGCGCGGTGATCCTGGGGCTCAGGCCCCGTG
ACTTCCATAAAAGCATGACGACCCACGCCGACCATCGCGTCTGGCAGGATGTCTACCACACCAGGCTGCACAATGGCATG
GTGGCTTATCTCAAGCTCAGCGTGGTCGACGACGTGCTGGTGGTTTCCTTCAAGGAGCTTTGA

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14957.10 Da        Isoelectric Point: 7.1658

>AT57989 WP_013234491.1 NZ_CP013136:c2842915-2842514 [Herbaspirillum seropedicae]
MKCPCCGAAELVHETRDLPYTYKGESTLIAQVKGDFCPACGEVLLDREHGDRYSELIGQFQRKVNAAYVDPAYIARVRRK
LDLDQREAGELFGGGVNAFSRYENGKTKPPLSLVKLFRLLDRHPDLLDEIRAA

Download         Length: 402 bp

>AT57989 NZ_CP013136:c2842915-2842514 [Herbaspirillum seropedicae]
ATGAAATGTCCTTGCTGCGGCGCAGCCGAACTGGTCCACGAAACACGTGACCTGCCCTATACCTACAAGGGCGAAAGCAC
CCTCATTGCCCAGGTGAAGGGGGACTTCTGTCCTGCCTGCGGCGAAGTCCTGCTCGATCGGGAGCATGGCGACCGCTACA
GCGAACTGATCGGGCAATTCCAGCGCAAGGTGAATGCGGCCTACGTGGACCCCGCCTACATAGCCCGGGTCCGGCGCAAG
CTCGATCTCGACCAGCGCGAGGCAGGCGAGCTCTTCGGCGGCGGCGTCAATGCCTTTTCCCGTTACGAGAACGGCAAGAC
CAAGCCGCCGCTCTCACTGGTCAAGCTGTTCAGGTTGCTGGACCGGCATCCCGACCTGCTGGACGAAATCCGCGCCGCCT
GA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References